An updated review of computer‐aided drug design and its application to COVID‐19
The recent outbreak of the deadly coronavirus disease 19 (COVID‐19) pandemic poses
serious health concerns around the world. The lack of approved drugs or vaccines continues …
serious health concerns around the world. The lack of approved drugs or vaccines continues …
COVID-19: characteristics and therapeutics
R Chilamakuri, S Agarwal - Cells, 2021 - mdpi.com
Novel coronavirus (COVID-19 or 2019-nCoV or SARS-CoV-2), which suddenly emerged in
December 2019 is still haunting the entire human race and has affected not only the …
December 2019 is still haunting the entire human race and has affected not only the …
A review of potential suggested drugs for coronavirus disease (COVID-19) treatment
The latest pandemic, coronavirus disease-2019 (COVID-19), is associated with high
prevalence and easy transmission, which is expanding globally with no conventional …
prevalence and easy transmission, which is expanding globally with no conventional …
Thyroid and COVID-19: a review on pathophysiological, clinical and organizational aspects
G Lisco, A De Tullio, E Jirillo, VA Giagulli… - Journal of …, 2021 - Springer
Background Thyroid dysfunction has been observed in patients with COVID-19, and
endocrinologists are requested to understand this clinical issue. Pandemic-related …
endocrinologists are requested to understand this clinical issue. Pandemic-related …
Structure-based optimization of ML300-derived, noncovalent inhibitors targeting the severe acute respiratory syndrome coronavirus 3CL protease (SARS-CoV-2 …
Starting from the MLPCN probe compound ML300, a structure-based optimization campaign
was initiated against the recent severe acute respiratory syndrome coronavirus (SARS-CoV …
was initiated against the recent severe acute respiratory syndrome coronavirus (SARS-CoV …
Oral antiviral treatments for COVID-19: opportunities and challenges
L Rahmah, SO Abarikwu, AG Arero, M Essouma… - Pharmacological …, 2022 - Springer
The use of antiviral COVID-19 medications can successfully inhibit SARS-CoV-2 replication
and prevent disease progression to a more severe form. However, the timing of antiviral …
and prevent disease progression to a more severe form. However, the timing of antiviral …
Curcumin inhibits in vitro SARS-CoV-2 infection in Vero E6 cells through multiple antiviral mechanisms
D Marín-Palma, JH Tabares-Guevara… - Molecules, 2021 - mdpi.com
Due to the scarcity of therapeutic approaches for COVID-19, we investigated the antiviral
and anti-inflammatory properties of curcumin against SARS-CoV-2 using in vitro models …
and anti-inflammatory properties of curcumin against SARS-CoV-2 using in vitro models …
Exploring diverse frontiers: Advancements of bioactive 4-aminoquinoline-based molecular hybrids in targeted therapeutics and beyond
Amongst heterocyclic compounds, quinoline and its derivatives are advantaged scaffolds
that appear as a significant assembly motif for developing new drug entities. Aminoquinoline …
that appear as a significant assembly motif for developing new drug entities. Aminoquinoline …
[HTML][HTML] Remdesivir efficacy in COVID-19 treatment: a randomized controlled trial
S Abd-Elsalam, M Salama, S Soliman… - … American Journal of …, 2021 - pmc.ncbi.nlm.nih.gov
To date, no antiviral therapy has shown proven clinical effectiveness in treating patients with
COVID-19. We assessed the efficacy of remdesivir in hospitalized Egyptian patients with …
COVID-19. We assessed the efficacy of remdesivir in hospitalized Egyptian patients with …
Coronavirus disease 2019 (COVID-19) pandemic across Africa: current status of vaccinations and implications for the future
The introduction of effective vaccines in December 2020 marked a significant step forward in
the global response to COVID-19. Given concerns with access, acceptability, and hesitancy …
the global response to COVID-19. Given concerns with access, acceptability, and hesitancy …