Failure of analgesic drugs in clinical development is common. Along with the current
“reproducibility crisis” in pain research, this has led some to question the use of animal …

These updated guidelines present a practical and logical approach to the assessment and
management of acute and chronic pain in canine and feline patients. Recognizing pain is …

Opioids are considered the gold standard to manage acute or chronic or mild to severe pain.
Tramadol is a widely prescribed analgesic drug for dogs and cats; it has a synthetic partial …

OBJECTIVE Toevaluate effects of gabapentin on activity levels and owner-perceived
mobility impairment and quality of life (QOL) in osteoarthritic geriatric cats. DESIGN Blinded …

OBJECTIVE To evaluate tramadol for treatment of signs of pain and impaired mobility in
geriatric cats with osteoarthritis. DESIGN Randomized controlled crossover trial. ANIMALS …

Background: Pain management for cats with degenerative joint disease (DJD) remains a
critical unmet need. Recent work has shown promise for a feline-specific anti-nerve growth …

Objectives This study aimed to (1) compare outcome assessments in normal and
osteoarthritic cats and (2) evaluate the analgesic efficacy of tramadol in feline osteoarthritis …

Opioids are the cornerstone for the treatment of acute pain in small animal patients. This is
primarily because of their remarkable safety profile, high efficacy, and benefit of reversibility …

The aim of this study was to develop oral lyophilisates with improved meloxicam (MEL)
dissolution, optimizing each step of the preparation by design of experiments. First …

Objectives The aim of the study was to determine if amantadine improves owner-identified
mobility impairment and quality of life associated with osteoarthritis in cats. Methods Using a …