Macrophages exist in various tissues, several body cavities, and around mucosal surfaces
and are a vital part of the innate immune system for host defense against many pathogens …

Fibrosis progression in the lung commonly results in impaired functional gas exchange,
respiratory failure, or even death. In addition to the aberrant activation and differentiation of …

The ECM (extracellular matrix) network plays a crucial role in cardiac homeostasis, not only
by providing structural support, but also by facilitating force transmission, and by transducing …

Macrophages respond to microbial ligands and various noxious cues by initiating an
inflammatory response aimed at eliminating the original pathogenic insult. Transition of …

The widespread use of biomaterials to support or replace body parts is increasingly
threatened by the risk of implant‐associated infections. In the quest for finding novel anti …

Scarring is part of the normal healing response to tissue injury in all organs and required to
rapidly repair acute damages, mostly with extracellular matrix. A variety of different cells are …

Cardiac macrophages represent a heterogeneous cell population with distinct origins,
dynamics, and functions. Recent studies have revealed that CC Chemokine Receptor 2 …

Macrophages and dendritic cells are myeloid cells that play critical roles in immune
responses. Macrophages help to maintain homeostasis through tissue regeneration and the …

Transient Receptor Potential (TRP) channels are a family of ion channels whose members
are distributed among all kinds of animals, from invertebrates to vertebrates. The importance …

Transient receptor potential vanilloid-type 4 (TRPV4) cation channel is widely expressed in
all tissues as well as in immune cells and its function as mechanosensitive Ca2+ channel …