Adult neurogenesis, the process by which neurons are generated in certain areas of the
adult brain, declines in an age-dependent manner and is one potential target for extending …

Zinc finger proteins (ZNF) are among the most abundant proteins in eukaryotic genomes. It
contains several zinc finger domains that can selectively bind to certain DNA or RNA and …

The recent, controversial approval of antibody-based treatments for Alzheimer's disease
(AD) is fueling a heated debate on the molecular determinants of this condition. The …

Alzheimer's disease (AD) is the most frequent type of dementia characterized by the
deposition of amyloid beta (Aβ) plaque and tau-neurofibrillary tangles (TNTs) in the brain …

Alzheimer's disease is a progressive neurodegenerative disorder and the most common
cause of dementia that principally affects older adults. Pathogenic factors, such as oxidative …

Background Epigenetics regulate gene expression without altering the DNA sequence.
Epigenetics targeted chemotherapeutic approach can be used to overcome treatment …

Efficient brain function requires as much as 20% of the total oxygen intake to support normal
neuronal cell function. This level of oxygen usage, however, leads to the generation of free …

Alzheimer's disease (AD) and type 2 diabetes mellitus (T2DM) are two prevalent conditions
that present considerable public health issue in aging populations worldwide. Recent …

Alzheimer's disease (AD) is one of the neurodegenerative diseases that leads to the
deposition of amyloid plaques in the neuropil as well as outside the cells in the brain leading …

Alzheimer's disease (AD), the leading cause of dementia, presents a significant global
health challenge with no known cure to date. Central to our understanding of AD …