Methane is a potent greenhouse gas that contributes significantly to climate change and is
primarily regulated in Nature by methanotrophic bacteria, which consume methane gas as …

Aerobic methanotrophs have long been known to play a critical role in the global carbon
cycle, being capable of converting methane to biomass and carbon dioxide. Interestingly …

Metal homeostasis poses a major challenge to microbes, which must acquire scarce
elements for core metabolic processes. Methanobactin, an extensively modified copper …

Aerobic methane-oxidizing bacteria (methanotrophs) have the unique ability to grow on
methane as their sole source of carbon and energy. They are ubiquitous in the environment …

Methane, the predominant element in natural gas and biogas, represents a promising
alternative to carbon feedstocks in the biotechnological industry due to its low cost and high …

Copper-binding metallophores, or chalkophores, play a role in microbial copper
homeostasis that is analogous to that of siderophores in iron homeostasis. The best-studied …

A nonribosomal peptide synthetase (NRPS) gene cluster (sfa) was identified in
Streptomyces thioluteus to direct the biosynthesis of the diisonitrile antibiotic SF2768. Its …

The iron-containing heterodimeric MbnBC enzyme complex plays a central role in the
biosynthesis of methanobactins (Mbns), ribosomally synthesized, posttranslationally …

Methanotrophs are potent natural producers of several bioactive secondary metabolites
(SMs) including isoprenoids, polymers, peptides, and vitamins. Cryptic biosynthetic gene …

Methanobactins (Mbns) are a family of copper-binding peptides involved in copper uptake
by methanotrophs, and are potential therapeutic agents for treating diseases characterized …