Overcoming skin barriers through advanced transdermal drug delivery approaches

V Phatale, KK Vaiphei, S Jha, D Patil, M Agrawal… - Journal of controlled …, 2022 - Elsevier
Upon exhaustive research, the transdermal drug delivery system (TDDS) has appeared as a
potential, well-accepted, and popular approach to a novel drug delivery system. Ease of …

[PDF][PDF] Physicochemical and biopharmaceutical aspects influencing skin permeation and role of SLN and NLC for skin drug delivery

EB Souto, JF Fangueiro, AR Fernandes, A Cano… - Heliyon, 2022 - cell.com
The skin is a complex and multifunctional organ, in which the static versus dynamic balance
is responsible for its constant adaptation to variations in the external environment that is …

Enhancement strategies for transdermal drug delivery systems: Current trends and applications

D Ramadon, MTC McCrudden, AJ Courtenay… - Drug delivery and …, 2021 - Springer
Transdermal drug delivery systems have become an intriguing research topic in
pharmaceutical technology area and one of the most frequently developed pharmaceutical …

Approaches for breaking the barriers of drug permeation through transdermal drug delivery

A Alexander, S Dwivedi, TK Giri, S Saraf, S Saraf… - Journal of controlled …, 2012 - Elsevier
Transdermal drug delivery system (TDDS) utilizes the skin as executable route for drug
administration but the foremost barrier against drug permeability is the stratum corneum and …

Sonophoresis in transdermal drug deliverys

D Park, H Park, J Seo, S Lee - Ultrasonics, 2014 - Elsevier
Transdermal drug delivery (TDD) has several significant advantages compared to oral drug
delivery, including elimination of pain and sustained drug release. However, the use of TDD …

Potential of combined ultrasound and microneedles for enhanced transdermal drug permeation: a review

T Han, DB Das - European Journal of Pharmaceutics and …, 2015 - Elsevier
Transdermal drug delivery (TDD) is limited by the outer layer of the skin, ie, the stratum
corneum. Research on TDD has become very active in the recent years and various …

Strategies for Improving Transdermal Administration: New Approaches to Controlled Drug Release

O Dumitriu Buzia, AM Păduraru, CS Stefan, M Dinu… - Pharmaceutics, 2023 - mdpi.com
In this work, we aim to address several strategies to improve transdermal drug delivery, such
as iontophoresis, sonophoresis, electroporation and micron. We also propose a review of …

Nanostructured lipid carriers containing chitosan or sodium alginate for co-encapsulation of antioxidants and an antimicrobial agent for potential application in wound …

S Costa-Fernandez, JKR Matos… - International journal of …, 2021 - Elsevier
The high incidence and costs of chronic wounds in the elderly have motivated the search for
innovations to improve product performance and the healing process while reducing costs …

Flexible microneedle array electrode using magnetorheological drawing lithography for bio-signal monitoring

L Ren, Q Jiang, Z Chen, K Chen, S Xu, J Gao… - Sensors and Actuators A …, 2017 - Elsevier
Monitoring and timely intervention are extremely important in the continuous home care.
Microneedle array electrode (MAE) have been employed for the long-term bio-signal …

Comparative evaluation of physical and chemical enhancement techniques for transdermal delivery of linagliptin

T Karve, AK Banga - International Journal of Pharmaceutics, 2024 - Elsevier
Linagliptin is a dipeptidyl peptidase-4 inhibitor used for the management of type-2 diabetes.
US FDA-approved products are available exclusively as oral tablets. The inherent …