DNA condensation by multivalent cations

VA Bloomfield - Biopolymers: Original Research on …, 1997 - Wiley Online Library
In the presence of multivalent cations, high molecular weight DNA undergoes a dramatic
condensation to a compact, usually highly ordered toroidal structure. This review begins with …

Spatial-temporal genome regulation in stress-response and cell-fate change

J Erenpreisa, A Giuliani, K Yoshikawa, M Falk… - International Journal of …, 2023 - mdpi.com
Complex functioning of the genome in the cell nucleus is controlled at different levels:(a) the
DNA base sequence containing all relevant inherited information;(b) epigenetic pathways …

Stretching of single collapsed DNA molecules

CG Baumann, VA Bloomfield, SB Smith… - Biophysical journal, 2000 - cell.com
The elastic response of single plasmid and lambda phage DNA molecules was probed
using optical tweezers at concentrations of trivalent cations that provoked DNA …

Discrete coil− globule transition of single duplex DNAs induced by polyamines

M Takahashi, K Yoshikawa… - The Journal of …, 1997 - ACS Publications
Recently, it has become clear that single, long duplex DNAs exhibit a large discrete
transition between elongated coil and compacted globule states. To obtain further insight …

Phase behavior of single DNA in mixed solvents

SM Mel'nikov, MO Khan, B Lindman… - Journal of the American …, 1999 - ACS Publications
Compaction of single large ds DNA chains in aqueous solution in the presence of primary
alcohols, acetone, and ethylene glycol has been studied experimentally with the use of a …

Coil− globule transition of DNA molecules induced by cationic surfactants: A dynamic light scattering study

RS Dias, J Innerlohinger, O Glatter… - The Journal of …, 2005 - ACS Publications
The compaction and aggregation of DNA induced by cationic surfactants was studied by
dynamic light scattering (DLS). Furthermore, the effect on surfactant-compacted DNA of the …

Compaction and decompaction of DNA in the presence of catanionic amphiphile mixtures

RS Dias, B Lindman, MG Miguel - The Journal of Physical …, 2002 - ACS Publications
The dissociation of DNA− cationic surfactant complexes with the addition of a negative
amphiphile was studied by fluorescence microscopy (FM). The unfolding of DNA molecules …

Collapse of polyelectrolyte macromolecules revisited

EY Kramarenko, AR Khokhlov, K Yoshikawa - Macromolecules, 1997 - ACS Publications
The simplest theory of the collapse transition of single polyelectrolyte chains in dilute
solutions is reconsidered. A novel feature of the new treatment is that the counterions can …

Highly effective compaction of long duplex DNA induced by polyethylene glycol with pendant amino groups

K Yoshikawa, Y Yoshikawa, Y Koyama… - Journal of the American …, 1997 - ACS Publications
By observing isolated long DNA chains with fluorescence microscopy, the collapsing
transition of individual single DNAs induced by polyethylene glycol with pendant amino …

Disappearance of the Negative Charge in Giant DNA witha Folding Transition

Y Yamasaki, Y Teramoto, K Yoshikawa - Biophysical Journal, 2001 - cell.com
In the present study we measure the electrophoretic mobility of giant T4 DNA (166 kbp) by
electrophoretic light scattering for the elongated and folded compact states at different …