Socioeconomic deprivation index is associated with psychiatric disorders: an observational and genome-wide gene-by-environment interaction analysis in the UK …
J Ye, Y Wen, X Sun, X Chu, P Li, B Cheng, S Cheng… - Biological …, 2021 - Elsevier
Background Psychiatric disorders are among the largest and fastest-growing categories of
the global disease burden. However, limited effort has been made to further elucidate …
the global disease burden. However, limited effort has been made to further elucidate …
Targeting GRK5 for treating chronic degenerative diseases
G protein-coupled receptors (GPCRs) are the largest family of cell-surface receptors and
they are responsible for the transduction of extracellular signals, regulating almost all …
they are responsible for the transduction of extracellular signals, regulating almost all …
Genetic Arg-304-his substitution in GRK5 protects against sepsis progression by alleviating NF-κB-mediated inflammation
M Xu, Y Shao, K Lin, Y Liu, Y Lin, Y Lin, R Yang… - International …, 2023 - Elsevier
Background Previous studies have demonstrated that G protein-coupled receptor kinase 5
(GRK5) exerts a pivotal regulatory effect on the inflammation associated with sepsis. The …
(GRK5) exerts a pivotal regulatory effect on the inflammation associated with sepsis. The …