[HTML][HTML] Urine proteomic signatures of histological class, activity, chronicity, and treatment response in lupus nephritis

A Fava, J Buyon, L Magder, J Hodgin, A Rosenberg… - JCI insight, 2024 - ncbi.nlm.nih.gov
Lupus nephritis (LN) is a pathologically heterogenous autoimmune disease linked to end-
stage kidney disease and mortality. Better therapeutic strategies are needed as only 30 …

KDOQI US commentary on the 2021 KDIGO clinical practice guideline for the management of glomerular diseases

LH Beck Jr, I Ayoub, D Caster, MJ Choi, J Cobb… - American Journal of …, 2023 - Elsevier
The KDIGO 2021 Clinical Practice Guideline for the Management of Glomerular Diseases
represents the first update to this set of recommendations since the initial set of KDIGO …

[HTML][HTML] Kidney Biopsy in Management of Lupus Nephritis: A Case-Based Narrative Review

S Rodriguez-Ramirez, N Wiegley, JM Mejia-Vilet - Kidney Medicine, 2024 - Elsevier
Kidney involvement in patients with lupus highly increases morbidity and mortality. In recent
years, several reports have emphasized the dissociation between clinical and histological …

Longitudinal patterns and predictors of response to standard-of-care therapy in lupus nephritis: data from the Accelerating Medicines Partnership Lupus Network

PM Izmirly, MY Kim, PM Carlucci, K Preisinger… - Arthritis Research & …, 2024 - Springer
Abstract Background Leveraging the Accelerating Medicines Partnership (AMP) Lupus
Nephritis (LN) dataset, we evaluated longitudinal patterns, rates, and predictors of response …

Long-term outcomes of lupus nephritis with low-level proteinuria: a multicentre, retrospective study

T Zoshima, S Hara, K Suzuki, M Yoshida… - …, 2023 - academic.oup.com
Objectives Reportedly, patients with LN and low-level proteinuria have favourable short-term
renal outcomes. We aimed to clarify the long-term renal outcomes and overall survival of …

Attainment of EULAR/ERA-EDTA targets of therapy with current immunosuppressive regimens and adjustments in treatment: a multicentre, real-life observational …

M Pappa, M Kosmetatou, A Pieta, M Nikoloudaki… - RMD open, 2024 - rmdopen.bmj.com
Objective To estimate real-life European Alliance of Associations for Rheumatology
(EULAR)/European Renal Association (ERA)-European Dialysis and Transplantation …

Efficacy of Voclosporin in Proliferative Lupus Nephritis with High Levels of Proteinuria

H Menn-Josephy, LS Hodge, V Birardi… - Clinical Journal of the …, 2023 - journals.lww.com
Background: In a phase 3 study of adults with active lupus nephritis, addition of voclosporin
to mycophenolate mofetil (MMF) and low-dose glucocorticoids led to significant …

Does the standard proteinuria cut-off for renal biopsy in lupus nephritis as per the current guidelines hold good for Asian population? A single-centre study from South …

S Padiyar, C As, M Gowri, J Mathew - Lupus, 2024 - journals.sagepub.com
Introduction Current rheumatology and nephrology society guidelines in lupus nephritis do
not recommend renal biopsy for proteinuria of less than 500 mg/24 h. This might lead to a …

Extrarenal symptoms associate with worse quality of life in patients enrolled in the AMP RA/SLE Lupus Nephritis Network

PM Carlucci, K Preisinger, KK Deonaraine… - …, 2024 - academic.oup.com
Objective Lupus nephritis (LN) can occur as an isolated component of disease activity or be
accompanied by diverse extrarenal manifestations. Whether isolated renal disease is …

Impact of baseline proteinuria level on long-term outcomes in lupus nephritis

F Kharouf, Q Li, LP Whittall Garcia, DD Gladman… - …, 2024 - academic.oup.com
Objectives Proteinuria is a marker of lupus nephritis (LN) activity and damage. We aimed to
explore the impact of baseline proteinuria level on long-term outcomes. Methods We …