Over 50 million people worldwide have epilepsy. In nearly 30% of these cases, epilepsy
remains unsatisfactorily controlled despite the availability of over 20 antiepileptic drugs …

Candidates for epilepsy surgery must undergo presurgical evaluation to establish whether
and how surgical treatment can stop seizures without causing neurological deficits. Various …

Responsive neurostimulation (RNS) devices, able to detect imminent seizures and to rapidly
deliver electrical stimulation to the brain, are effective in reducing seizures in some patients …

High‐frequency oscillations (HFO s) are a type of brain activity that is recorded from brain
regions capable of generating seizures. Because of the close association of HFO s with …

In∼ 20 million people with drug-resistant epilepsy, focal seizures originating in
dysfunctional brain networks will often evolve and spread to surrounding tissue, disrupting …

Localizing neuronal patterns that generate pathological brain signals may assist with tissue
resection and intervention strategies in patients with neurological diseases. Precise …

Patients with drug-resistant epilepsy often require surgery to become seizure-free. While
laser ablation and implantable stimulation devices have lowered the morbidity of these …

The epileptic network is characterized by pathologic, seizure-generating 'foci'embedded in a
web of structural and functional connections. Clinically, seizure foci are considered optimal …

Objective Intraoperative electrocorticography (ECoG) can be used to delineate the resection
area in epilepsy surgery. High‐frequency oscillations (HFOs; 80–500 Hz) seem better …

Brain‐computer interfaces (BCIs) aim to help paralysed patients to interact with their
environment by controlling external devices using brain activity, thereby bypassing the …