Importance of thymoquinone, sulforaphane, phloretin, and epigallocatechin and their health benefits

MH Shahrajabian, W Sun - Letters in Drug Design & Discovery, 2024 - benthamdirect.com
Natural products have a broad diversity of multidimensional chemical formations, which play
an important role, and indicate the crucial nature as a golden source for gaining herbal drug …

Cardiotoxicity of some pesticides and their amelioration

Y El-Nahhal, I El-Nahhal - Environmental Science and Pollution Research, 2021 - Springer
Pesticides are used to control pests that harm plants, animals, and humans. Their
application results in the contamination of the food and water systems. Pesticides may cause …

Antioxidant and Anti-Inflammatory Properties of Nigella sativa Oil in Human Pre-Adipocytes

L Bordoni, D Fedeli, C Nasuti, F Maggi, F Papa… - Antioxidants, 2019 - mdpi.com
The oil obtained from the seeds of Nigella sativa L.(N. sativa), also known as black cumin, is
frequently used in the Mediterranean area for its anti-inflammatory, anti-oxidant, and anti …

[HTML][HTML] Thymoquinone suppresses invasion and metastasis in bladder cancer cells by reversing EMT through the Wnt/β-catenin signaling pathway

M Zhang, H Du, L Wang, Y Yue, P Zhang… - Chemico-biological …, 2020 - Elsevier
Epithelial mesenchymal transformation plays a crucial role in the metastasis of bladder
cancer, which makes bladder cancer difficult to cure. Bladder cancer is the most common …

Evaluation of the hepatoprotective effects of curcumin and nanocurcumin against paraquat‐induced liver injury in rats: Modulation of oxidative stress and Nrf2 pathway

N Kheiripour, A Plarak, A Heshmati… - … of Biochemical and …, 2021 - Wiley Online Library
Paraquat (PQ) is a widely used herbicide all over the world, which is highly toxic for animals
and humans. Its cytotoxicity is based on reactive radical generation. The aim of this study is …

Toxicology of paraquat and pharmacology of the protective effect of 5-hydroxy-1-methylhydantoin on lung injury caused by paraquat based on metabolomics

L Gao, H Yuan, E Xu, J Liu - Scientific reports, 2020 - nature.com
Paraquat (PQ) is a non-selective herbicide and is exceedingly toxic to humans. The
mechanism of PQ toxicity is very complex and has not been clearly defined. There is no …

Biochemical and Histological Evidence on the Protective Effects of Allium hirtifolium Boiss (Persian Shallot) as an Herbal Supplement in Cadmium‐Induced …

N Omidifar, A Nili-Ahmadabadi… - Evidence‐Based …, 2020 - Wiley Online Library
Background and Objectives. Allium hirtifolium Boiss (Persian shallot), as an edible
vegetable, has several pharmacological properties including antimicrobial, anti …

Protective efficacy of thymoquinone or ebselen separately against arsenic-induced hepatotoxicity in rat

D Al Aboud, RS Baty, KF Alsharif, KE Hassan… - … Science and Pollution …, 2021 - Springer
Arsenic (As) exposure is associated with adverse health outcomes to the living organisms. In
the present study, the hepato-protective ability of thymoquinone (TQ), the active principle of …

Immediate and late systemic and lung effects of inhaled paraquat in rats

F Amin, A Roohbakhsh, A Memarzia… - Journal of Hazardous …, 2021 - Elsevier
The immediate and the late effects of inhaled Paraquat (PQ) on systemic and lung
inflammation and oxidative stress were investigated. Rats were exposed to saline (control …

Protective Effects of Thymoquinone, an Active Compound of Nigella sativa, on Rats with Benzo(a)pyrene-Induced Lung Injury through Regulation of Oxidative Stress …

MA Alzohairy, AA Khan, MA Alsahli, SA Almatroodi… - Molecules, 2021 - mdpi.com
Benzopyrene [B (a) P] is a well-recognized environmental carcinogen, which promotes
oxidative stress, inflammation, and other metabolic complications. In the current study, the …