Cancer stem cells (CSCs), known also as tumor-initiating cells, are quiescent, pluripotent,
self-renewing neoplastic cells that were first identified in hematologic tumors and soon after …

Gliomas are the most common primary brain tumors in adults. They arise in the glial tissue
and primarily occur in the brain. Low‐grade tumors of World Health Organization (WHO) …

Glioblastoma, a grade IV astrocytoma, is regarded as the most aggressive primary brain
tumour with an overall median survival of 16.0 months following the standard treatment …

Glioblastoma multiforme (GBM) is one of the most lethal forms of primary brain tumors.
Glioblastoma stem cells (GSCs) play an undeniable role in tumor development by activating …

Neural stem cells (NSCs) were described for the first time more than two decades ago for
their ability to differentiate into all neural cell lineages. The isolation of NSCs from adults and …

Hyaluronic acid (HA) is a Glycosaminoglycan made of disaccharide units containing N-
acetyl-D-glucosamine and glucuronic acid. Its molecular mass can reach 10 MDa and its …

Glioblastoma is an aggressive tumor and is associated with a dismal prognosis. The
availability of few active treatments as well as the inexorable recurrence after surgery are …

Non-coding RNAs (ncRNAs) have been recognized as pivotal regulators of transcriptional
and post-transcriptional gene modulation, exerting a profound influence on a diverse array …

Glioblastoma multiforme (GBM) is the most prevalent form of brain tumor, which generally
has a poor prognosis. According to consensus, recurrence of the tumor and chemotherapy …

Abstract Background Glioblastomas (GBMs) are the main primary brain tumors in adults with
almost 100% recurrence rate. Patients with lateral ventricle proximal GBMs (LV-GBMs) …