Metabolomics in hepatocellular carcinoma: From biomarker discovery to precision medicine

X Wu, Z Wang, L Luo, D Shu, K Wang - Frontiers in Medical …, 2023 - frontiersin.org
Hepatocellular carcinoma (HCC) remains a global health burden, and is mostly diagnosed
at late and advanced stages. Currently, limited and insensitive diagnostic modalities …

Metabolomics in viral hepatitis: Advances and review

J Yang, D Wang, Y Li, H Wang, Q Hu… - Frontiers in Cellular and …, 2023 - frontiersin.org
Viral hepatitis is a major worldwide public health issue, affecting hundreds of millions of
people and causing substantial morbidity and mortality. The majority of the worldwide …

Abdominal ultrasound and alpha‐foetoprotein for the diagnosis of hepatocellular carcinoma in adults with chronic liver disease

A Colli, T Nadarevic, D Miletic, V Giljaca… - Cochrane Database …, 2021 - cochranelibrary.com
Background Hepatocellular carcinoma (HCC) occurs mostly in people with chronic liver
disease and ranks sixth in terms of global instances of cancer, and fourth in terms of cancer …

Molecular and metabolic phenotyping of hepatocellular carcinoma for biomarker discovery: a meta-analysis

NH Anh, NP Long, YJ Min, Y Ki, SJ Kim, CW Jung… - Metabolites, 2023 - mdpi.com
Identifying and translating hepatocellular carcinoma (HCC) biomarkers from bench to
bedside using mass spectrometry-based metabolomics and lipidomics is hampered by …

Characterization of Salivary and Plasma Metabolites as Biomarkers for HCC: A Pilot Study

CE Hershberger, R Raj, A Mariam, N Aykun… - Cancers, 2023 - mdpi.com
Simple Summary Hepatocellular carcinoma is diagnosed using ultrasound and blood-
biomarker AFP, which can miss up to 40% of diagnoses, delaying the treatment of these …

[HTML][HTML] Characteristics of Hepatocellular‎ Carcinoma in Egyptian Patients:‎ A Single Center Pilot Study‎

IM Elkenawy, M El-Bendary… - … -Egyptian Journal of …, 2022 - aeji.journals.ekb.eg
Background and study aim: Hepatocellular‏‏ Carcinoma (HCC) is regarded as one of the most‎
widespread leading causes of mortality annually. The most‎ frequent risk factors for HCC are …

[HTML][HTML] Metabolomic biomarkers for hepatocellular carcinoma: A systematic review

N Feng, F Yu, F Yu, Y Feng, X Zhu, Z Xie, Y Zhai - Medicine, 2022 - journals.lww.com
Background: Hepatocellular carcinoma (HCC) is a highly malignant cancer which lack of
effective diagnosis and prognosis biomarkers, therefore surging studies focused on the …

Metabolomics in cirrhosis: Recent advances and opportunities

Y Luo, C Zhang, X Nong, Y Gao, L Wang, G Ji, T Wu - Clinica Chimica Acta, 2024 - Elsevier
Liver cirrhosis (LC) represents a significant hepatic disorder that persistently commands the
attention of the scientific community, especially concerning its pathogenesis and therapeutic …

[PDF][PDF] 病毒性肝炎肝硬化患者早期肝细胞癌代谢变化及其与衰老和酶活性的关系

蒋黎, 朱研, 刘慧敏, 吕化杰, 刘明 - 安徽医科大学学报, 2022 - aydxb.cn
摘要目的探讨病毒性肝炎肝硬化患者早期肝细胞癌代谢变化及其与衰老和酶活性的关系.
方法以140 例患者为研究对象, 根据诊断结果分为肝硬化组(LC 组), 肝硬化肝细胞癌组(CLH 组) …

[HTML][HTML] Altered Metabolites in Hepatocellular Carcinoma (HCC) Paving the Road for Metabolomics Signature and Biomarkers for Early Diagnosis of HCC

HS Al-Amodi, HF Kamel - Cureus, 2024 - pmc.ncbi.nlm.nih.gov
Globally, hepatocellular carcinoma (HCC) is one of the most commonly encountered
cancers. Because the current early diagnostic tests for HCC are not very sensitive, most …