The interplay of signaling pathways with miRNAs in cholangiocarcinoma pathogenicity and targeted therapy

MB Zaki, AI Abulsoud, SS Elshaer, D Fathi… - … -Research and Practice, 2023 - Elsevier
Cholangiocarcinoma (CCA), the second most frequent liver cancer after hepatocellular
carcinoma, has been rising worldwide in recent epidemiological research. This neoplasia's …

[HTML][HTML] Liquid biopsy in cholangiocarcinoma: Current status and future perspectives

G Rompianesi, M Di Martino… - World Journal of …, 2021 - ncbi.nlm.nih.gov
Cholangiocarcinoma (CCA) are a heterogeneous group of tumors in terms of aetiology,
natural history, morphological subtypes, molecular alterations and management, but all …

[HTML][HTML] Prognostic and predictive molecular markers in cholangiocarcinoma

S Pavicevic, S Reichelt, D Uluk, I Lurje, C Engelmann… - Cancers, 2022 - mdpi.com
Simple Summary Cholangiocarcinoma (CCA) is a heterogenous and aggressive
malignancy of the intra-and extrahepatic biliary tract, marked by a steeply rising incidence …

[HTML][HTML] Biliary tract cancers: treatment updates and future directions in the era of precision medicine and immuno-oncology

A Manne, E Woods, A Tsung, A Mittra - Frontiers in Oncology, 2021 - frontiersin.org
The effective management of biliary tract cancers (BTCs) has been hampered by limited
options for systemic therapy. In recent years, the focus on precision medicine has made …

[HTML][HTML] Next-generation biomarkers for cholangiocarcinoma

PM Rodrigues, A Vogel, M Arrese, DC Balderramo… - Cancers, 2021 - mdpi.com
Simple Summary Early and non-invasive diagnosis of cholangiocarcinoma (CCA) is still
challenging, thus largely contributing to the increased mortality rates observed worldwide …

[HTML][HTML] Micro-RNA in cholangiocarcinoma: implications for diagnosis, prognosis, and therapy

A Barbato, F Piscopo, M Salati… - Journal of Molecular …, 2022 - mdpi.com
Bile-duct cancers (BDC) are a group of solid tumors arising from the biliary tree. Despite
their classification as rare cancers, the incidence of BDC is increasing worldwide. Poor …

[HTML][HTML] The role of microRNAs in cholangiocarcinoma

T Shi, A Morishita, H Kobara, T Masaki - International Journal of …, 2021 - mdpi.com
Cholangiocarcinoma (CCA), an aggressive malignancy, is typically diagnosed at an
advanced stage. It is associated with dismal 5-year postoperative survival rates, generating …

[HTML][HTML] Biliary Strictures and Cholangiocarcinoma–Untangling a Diagnostic Conundrum

A Ney, A Garcia-Sampedro, G Goodchild… - Frontiers in …, 2021 - frontiersin.org
Cholangiocarcinoma is an uncommon and highly aggressive biliary tract malignancy with
few manifestations until late disease stages. Diagnosis is currently achieved through a …

Small but mighty: How microRNAs drive the deadly progression of cholangiocarcinoma

AT Jalil, MA Abdulhadi, LR Al-Ameer… - … -Research and Practice, 2023 - Elsevier
Cholangiocarcinoma, also referred to as CCA, is a highly complex epithelial malignancy that
can impact various organs and regions of the body, including the perihilar, intrahepatic, and …

Clinical impact of bile‐derived exosomal microRNAs as novel diagnostic and prognostic biomarkers for biliary tract cancers

M Yoshida, H Yukawa, K Hayashi, I Naitoh… - Cancer …, 2023 - Wiley Online Library
Sampling of bile juice during endoscopic retrograde cholangiopancreatography (ERCP) has
potential benefit of being amenable to the identification of novel biomarkers in liquid biopsy …