Cognitive dysfunction in major depression and Alzheimer's disease is associated with hippocampal–prefrontal cortex dysconnectivity

D Sampath, M Sathyanesan… - … disease and treatment, 2017 - Taylor & Francis
Cognitive dysfunction is prevalent in psychiatric disorders. Deficits are observed in multiple
domains, including working memory, executive function, attention, and information …

Going round in circles—The Papez circuit in Alzheimer's disease

G Forno, A Lladó, M Hornberger - European Journal of …, 2021 - Wiley Online Library
The hippocampus is regarded as the pivotal structure for episodic memory symptoms
associated with Alzheimer's disease (AD) pathophysiology. However, what is often …

BolT: Fused window transformers for fMRI time series analysis

HA Bedel, I Sivgin, O Dalmaz, SUH Dar, T Çukur - Medical image analysis, 2023 - Elsevier
Deep-learning models have enabled performance leaps in analysis of high-dimensional
functional MRI (fMRI) data. Yet, many previous methods are suboptimally sensitive for …

Stimulation of the posterior cingulate cortex impairs episodic memory encoding

VS Natu, JJ Lin, A Burks, A Arora… - Journal of …, 2019 - Soc Neuroscience
Neuroimaging experiments implicate the posterior cingulate cortex (PCC) in episodic
memory processing, making it a potential target for responsive neuromodulation strategies …

Cholinergic denervation patterns across cognitive domains in Parkinson's disease

S van der Zee, MLTM Müller, P Kanel… - Movement …, 2021 - Wiley Online Library
Background The cholinergic system plays a key role in cognitive impairment in Parkinson's
disease (PD). Previous acetylcholinesterase positron emission tomography imaging studies …

Neural mechanisms of emotional health in traumatic brain injury patients undergoing rTMS treatment

T Sultana, MA Hasan, X Kang, V Liou-Johnson… - Molecular …, 2023 - nature.com
Emotional dysregulation such as that seen in depression, are a long-term consequence of
mild traumatic brain injury (TBI), that can be improved by using neuromodulation treatments …

How to build a functional connectomic biomarker for mild cognitive impairment from source reconstructed MEG resting-state activity: the combination of ROI …

SI Dimitriadis, ME López, R Bruña, P Cuesta… - Frontiers in …, 2018 - frontiersin.org
Our work aimed to demonstrate the combination of machine learning and graph theory for
the designing of a connectomic biomarker for mild cognitive impairment (MCI) subjects using …

Verbal memory formation across PET-based Braak stages of tau accumulation in Alzheimer's disease

J Fernández Arias, J Therriault, E Thomas… - Brain …, 2023 - academic.oup.com
A classical early sign of typical Alzheimer's disease is memory decline, which has been
linked to the aggregation of tau in the medial temporal lobe. Verbal delayed free recall and …

Longitudinal effects of aging on 18F-FDG distribution in cognitively normal elderly individuals

K Ishibashi, A Onishi, Y Fujiwara, K Oda, K Ishiwata… - Scientific reports, 2018 - nature.com
Previous studies of aging effects on fluorine-18-labeled fluorodeoxyglucose (18F-FDG)
distribution have employed cross-sectional designs. We examined aging effects on 18F …

Levetiracetam increases hippocampal blood flow in Alzheimer's disease as measured by arterial spin labelling MRI

DZ Press, CS Musaeus, L Zhao… - Journal of …, 2023 - journals.sagepub.com
Background: Patients with Alzheimer's disease (AD) have an increased risk of developing
epileptiform discharges, which is associated with a more rapid rate of progression. This …