Mitocanic Di-and triterpenoid rhodamine B conjugates

S Hoenke, I Serbian, HP Deigner, R Csuk - Molecules, 2020 - mdpi.com
The combination of the “correct” triterpenoid, the “correct” spacer and rhodamine B (RhoB)
seems to be decisive for the ability of the conjugate to accumulate in mitochondria. So far …

Mitochondria-affecting small molecules ameliorate proteostasis defects associated with neurodegenerative diseases

E Tjahjono, J Pei, AV Revtovich, TJE Liu, A Swadi… - Scientific reports, 2021 - nature.com
Macroautophagic recycling of dysfunctional mitochondria, known as mitophagy, is essential
for mitochondrial homeostasis and cell viability. Accumulation of defective mitochondria and …

Precise tailoring of thermoresponsive characteristics: Revealing ATRP opportunities for controlled poly (ethylene glycol)-based monomers composition in cyclodextrin …

M Klamut, I Zaborniak, J Bałbustyn, M Niemiec… - Polymer, 2024 - Elsevier
Star-shaped copolymers consisting of centrally located β-cyclodextrin and fifteen side chains
containing di (ethylene glycol) methyl ether methacrylate (DEGMA) and poly (ethylene …

Novel mitochondria-targeting compounds selectively kill human leukemia cells

SB Panina, J Pei, N Baran, E Tjahjono, S Patel… - Leukemia, 2022 - nature.com
Acute myeloid leukemia (AML) is a heterogeneous group of aggressive hematological
malignancies commonly associated with treatment resistance, high risk of relapse, and …

Quantitative cytotoxicity analysis of antibacterial Janus nanoparticles in immune and cancer cells

B Johnson, M Peck, H Richman… - …, 2024 - f1000research.com
Background Nanoparticles (NPs) hold promise as alternatives to antibiotics in the fight
against multi-drug-resistant bacteria. However, concerns about their cytotoxicity, particularly …

Cytotoxic Effect of Bajong LN Rice Methanol Extract on Human Squamous Cell Carcinoma, ORL-48

VN Ahmad, NAH Mohamed, Z Amom… - Malaysian Applied …, 2024 - jms.mabjournal.com
Oral squamous cell carcinoma (OSCC), a major oral cancer, significantly challenges
treatments and impacts patient quality of life; current therapies often cause severe side …

[PDF][PDF] LDH as a risk factor for IHD

AR Ashour - ijdmsrjournal.com
In the global health setting, trauma is identified as the primary cause of mortality and
impairment among the individuals (Johansson et al., 2011), where about 40% of the trauma …

Small Molecule Stabilization of PINK-1/PINK1 Improves Neurodegenerative Disease

E Tjahjono, J Pei, AV Revtovich, TJE Liu, A Swadi… - bioRxiv, 2021 - biorxiv.org
Macroautophagic recycling of dysfunctional mitochondria, known as mitophagy, is essential
for mitochondrial homeostasis and cell viability. Accumulation of defective mitochondria and …