Monoamine oxidase-B inhibitors for the treatment of Parkinson's disease: past, present, and future
YY Tan, P Jenner, SD Chen - Journal of Parkinson's Disease, 2022 - content.iospress.com
Abstract Monoamine oxidase-B (MAO-B) inhibitors are commonly used for the symptomatic
treatment of Parkinson's disease (PD). MAO-B inhibitor monotherapy has been shown to be …
treatment of Parkinson's disease (PD). MAO-B inhibitor monotherapy has been shown to be …
Cellular stress responses in radiotherapy
Radiotherapy is one of the major cancer treatment strategies. Exposure to penetrating
radiation causes cellular stress, directly or indirectly, due to the generation of reactive …
radiation causes cellular stress, directly or indirectly, due to the generation of reactive …
Monoamine oxidase isoenzymes: genes, functions and targets for behavior and cancer therapy
JC Shih - Journal of Neural Transmission, 2018 - Springer
Monoamine oxidase (MAO) catalyzes the oxidative deamination of monoamine
neurotransmitters and dietary amines. Two pharmacological types with different substrate …
neurotransmitters and dietary amines. Two pharmacological types with different substrate …
Monoamine oxidase (MAO) as a potential target for anticancer drug design and development
Monoamine oxidases (MAOs) are oxidative enzymes that catalyze the conversion of
biogenic amines into their corresponding aldehydes and ketones through oxidative …
biogenic amines into their corresponding aldehydes and ketones through oxidative …
[HTML][HTML] Tryptophan-related dipeptides in fermented dairy products suppress microglial activation and prevent cognitive decline
Y Ano, Y Yoshino, T Kutsukake, R Ohya… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
The rapid growth in aging populations has made prevention of age-related memory decline
and dementia a high priority. Several epidemiological and clinical studies have concluded …
and dementia a high priority. Several epidemiological and clinical studies have concluded …
Novel approaches to the discovery of selective human monoamine oxidase-B inhibitors: is there room for improvement?
P Guglielmi, S Carradori… - Expert Opinion on …, 2019 - Taylor & Francis
Introduction: Selective monoamine oxidase-B (MAO-B) inhibitors are currently used as
coadjuvants for the treatment of early motor symptoms in Parkinson's disease. They can …
coadjuvants for the treatment of early motor symptoms in Parkinson's disease. They can …
TFAP2C-mediated upregulation of TGFBR1 promotes lung tumorigenesis and epithelial–mesenchymal transition
TFAP2C (transcription factor-activating enhancer-binding protein 2C) expression has been
positively correlated with poor prognosis in patients with certain types of cancer, but the …
positively correlated with poor prognosis in patients with certain types of cancer, but the …
Challenging the anticolorectal cancer capacity of quinoxaline-based scaffold via triazole ligation unveiled new efficient dual VEGFR-2/MAO-B inhibitors
Monoamine oxidases (MAOs) and vascular endothelial growth factor receptor-2 (VEGFR-2)
are promoters of colorectal cancer (CRC) and central signaling nodes in epithelial …
are promoters of colorectal cancer (CRC) and central signaling nodes in epithelial …
RNF138-mediated ubiquitination of rpS3 is required for resistance of glioblastoma cells to radiation-induced apoptosis
An interaction between ribosomal protein S3 (rpS3) and nuclear factor kappa B or
macrophage migration inhibitory factor in non-small-cell lung cancer is responsible for …
macrophage migration inhibitory factor in non-small-cell lung cancer is responsible for …
TRAF4 promotes lung cancer aggressiveness by modulating tumor microenvironment in normal fibroblasts
Normal fibroblasts surrounding tumor cells play a crucial role in cancer progression through
formation of the tumor microenvironment. Because factors secreted from normal fibroblasts …
formation of the tumor microenvironment. Because factors secreted from normal fibroblasts …