There is a growing body of evidence from both observational and randomised trials
implicating integrase inhibitors, particularly dolutegravir and bictegravir, with the …

Objective To synthesize evidence on the association between human immunodeficiency
virus (HIV) infection and cognitive impairment in older adults. Design Meta-analysis …

Background Neurocognitive impairment (NCI) in people with HIV (PWH) on antiretroviral
therapy (ART) is common and may result from persistent HIV replication in the central …

Objective Chronic inflammation and vascular dysfunction (eg, chronic endothelial activation)
are related yet dissociable mechanisms of HIV-associated neurocognitive impairment (NCI) …

Despite advancements in antiretroviral therapy, mild cognitive deficits persist in nearly half of
people with HIV (PWH). The profile of impairment in HIV is highly variable with deficits …

In this fifth decade of the human immunodeficiency virus (HIV) epidemic, central nervous
system (CNS) complications including cognitive impairment and mental health remain a …

Background Excess weight gain is an important health concern among people with HIV
(PWH) on antiretroviral therapy (ART). The extent to which ART contributes to body mass …

HIV-associated neurocognitive impairment (HIV-NCI) affects 15%–50% of people with HIV
(PWH), despite viral suppression with antiretroviral therapy (ART). HIV neuropathogenesis is …

Objective: Cognitive deficits are common among people with HIV (PWH), even when virally
suppressed. We identified cognitive profiles among virally suppressed PWH and determined …

At-risk alcohol use is a significant risk factor associated with multisystemic
pathophysiological effects leading to multiorgan injury and contributing to 5.3% of all deaths …