Hypertrophic scars and keloids are fibroproliferative disorders that may arise after any deep
cutaneous injury caused by trauma, burns, surgery, etc. Hypertrophic scars and keloids are …

The global increase of cutaneous wounds imposes huge health and financial burdens on
patients and society. Despite improved wound healing outcomes, conventional wound …

BACKGROUND Keloid and hypertrophic scars represent an aberrant response to the wound
healing process. These scars are characterized by dysregulated growth with excessive …

Scar formation is an intractable medical problem that appears after skin wounds have
healed. Recent research has shown that exosomes secreted by human adipose …

The treatment for diabetic ulcers still remains a big clinic challenge owing to the adverse
repair microenvironment. Bioactive glasses (BGs) play an important role in the late stages of …

While considerable progress has been made towards understanding the complex processes
and pathways that regulate human wound healing, regenerative medicine has been unable …

Background: Scars represent the visible sequelae of trauma, injury, burn, or surgery. They
may induce distress in the patient because of their aesthetically unpleasant appearance …

Keloid disease is a benign, yet locally aggressive and recurrent cutaneous fibroproliferative
condition characterised by excessive scarring. Unique to humans, keloids represent the end …

Tissue regeneration repairs the fabric of the skin to maintain homeostasis after injury. The
expression and proliferation of extracellular matrix (ECM) molecules in the dermis, mediated …

Currently available tissue engineered skin-equivalents fail to replicate anatomically relevant
features, eg undulated morphology of the dermal-epidermal junction, resulting in inadequate …