Asthma is a clinical syndrome caused by heterogeneous underlying mechanisms with some
of them having a strong genetic component. It is known that up to 82% of atopic asthma has …

Background Preventing poor childhood asthma control is crucial for short-term and long-
term respiratory health. This study evaluated associations between perinatal and early-life …

Background The innate mechanisms associated with viral exacerbations in preschool
children with recurrent wheezing are not understood. Objective We sought to assess …

Asthma is one of the most common chronic disease affecting children, and it often starts in
infancy and preschool years. In previous birth cohorts, frequent wheezing in early life was …

Increasingly, clinical practice guidelines advocate a precision medicine–based approach to
care for asthma. This focus requires knowledge of not only different asthma phenotypes and …

Background Bronchial asthma, the most prevalent chronic inflammatory airway disease in
children, exhibits a concerning rise in both incidence and prevalence. Asthma biomarkers …

Background The potential influence of asthma control in early life on long-term outcomes in
childhood remains largely unknown. Objective To examine whether asthma control …

Aim To describe the relationship between loss of control events in preschoolers with asthma
and persistence of disease. Methods We reviewed medical records of children< 6 years …

In preschoolers, asthma control is assessed clinically using history and physical
examination. In certain centres, oscillometry is used to support clinical assessment; yet its …

Nearly all asthma predictive tools estimate the future risk of asthma development. However,
there is no tool to predict the probability of successful ICS cessation at an early age …