Gram-negative bacteria decorate their outermost surface structure, lipopolysaccharide, with
elaborate chemical moieties, which effectively disguises them from immune surveillance and …

The concept of immunizing against gonorrhea has received renewed interest because of the
recent emergence of strains of Neisseria gonorrhoeae that are resistant to most currently …

Neisseria meningitidis is an important cause of septicemia and meningitis. To cause
disease, the bacterium must successfully survive in the bloodstream where it has to avoid …

Complement forms an important arm of innate immunity against invasive meningococcal
infections. Binding of the alternative complement pathway inhibitor factor H (fH) to fH-binding …

Complement forms a key arm of innate immune defenses against gonococcal infection.
Sialylation of gonococcal lipo-oligosaccharide, or expression of porin 1A (Por1A) protein …

The host complement system plays an important role in protection against infections.
Several human-pathogenic microbes were shown to acquire host complement regulators …

Neisseria gonorrhoeae causes the sexually transmitted infection gonorrhea, while Neisseria
meningitidis is an important cause of bacterial meningitis and sepsis. Complement is a …

Two pathogenic species within the genus N eisseria cause the diseases gonorrhoea and
meningitis. While vaccines are available to protect against four N. meningitidis serogroups …

The emergence of ceftriaxone-resistant strains of Neisseria gonorrhoeae may herald an era
of untreatable gonorrhea. Vaccines against this infection are urgently needed. The 2C7 …

Infection with the human-specific bacterial pathogen Neisseria gonorrhoeae triggers a
potent, local inflammatory response driven by polymorphonuclear leukocytes (neutrophils or …