Recent advances in the molecular understanding of the porphyrias now offer specific
diagnosis and precise definition of the types of genetic mutations involved in the disease …

Examination of the skin and nails can reveal many abnormalities in patients with end-stage
renal disease that precede or follow initiation of dialysis treatment or kidney transplantation …

The treatment of porphyria cutanea tarda (PCT) in patients with chronic renal failure poses a
therapeutic challenge. In the absence of renal failure, phlebotomy and oral antimalarials …

There are seven porphyrias which are caused by defective functions of the enzymes in the
haem biosynthesis. Pathogenic mechanisms and symptoms differ greatly in individual …

The porphyrias are diverse in pathophysiology, clinical presentation, severity, and
prognosis, presenting a diagnostic and therapeutic challenge. Although not easily curable …

Einleitung Porphyrine sind lebenswichtige Farbstoffe, die die Grundstruktur des Häm und
des Chlorophyll bilden. Die Synthese des Häm erfolgt, ausgehend von Succinyl-Coenzym A …

Certain types of porphyria have an increased incidence of malignant disease. In addition,
patients with all forms of porphyria may develop malignant disease as a 'normal life event' …

End-stage renal failure and long-term hemodialysis (HD) treatment promote the
development of genetically conditioned porphyria cutanea tarda (PCT). Iron overload is …

To assess the capability of three different membranes to remove porphyrins, plasma and
dialysate porphyrin levels were fluorometrically measured in 10 patients with end-stage …

Increased plasma porphyrins have been described in patients with chronic renal failure
(CRF). We measured plasma levels of porphyrins and the activity in erythrocytes of …