The importance of reactive oxygen species (ROS) has been gradually acknowledged over
the last four decades. Initially perceived as unwanted products of detrimental oxidative …

Regeneration is the process of replacing/restoring a damaged cell/tissue/organ to its full
function and is limited respecting complexity of specific organ structures and the level of …

Osteoarthritis (OA) is a multifactorial and increasingly prevalent degenerative disease that
affects the whole joint. The pathogenesis of OA is poorly understood and there is a lack of …

Lipids, phospholipids and cholesterol in particular, are the predominant components of the
plasma membrane, wherein multidrug efflux transporters of the ATP-binding cassette (ABC) …

(1) Background: The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) disease (COVID-19) in China at the end of 2019 has caused a large global outbreak …

It is well known that oxidative stress and lipid peroxidation (LPO) play a role in physiology
and pathology. The most studied LPO product with pleiotropic capabilities is 4 …

Lipid peroxidation, including its prominent byproducts such as malondialdehyde (MDA) and
4-hydroxy-2-nonenal (4-HNE), has long been linked with worsened metabolic health in …

Oxidative stress occurs when the production of oxidants surpasses the antioxidant capacity
in living cells. Oxidative stress is implicated in a number of pathological conditions such as …

Our common knowledge on oxidative stress has evolved substantially over the years, being
focused mostly on the fundamental chemical reactions and the most relevant chemical …

(1) Background: Cancer is one of the leading causes of mortality worldwide. Radiotherapy
and chemotherapy attempt to kill tumor cells by different mechanisms mediated by an …