Salmonellae interactions with host processes

DL LaRock, A Chaudhary, SI Miller - Nature Reviews Microbiology, 2015 - nature.com
Salmonellae invasion and intracellular replication within host cells result in a range of
diseases, including gastroenteritis, bacteraemia, enteric fever and focal infections. In recent …

Salmonella enterica Serovar Typhi and the Pathogenesis of Typhoid Fever

G Dougan, S Baker - Annual review of microbiology, 2014 - annualreviews.org
Salmonella enterica serovar Typhi, the cause of typhoid, is host restricted to humans. S.
Typhi has a monophyletic population structure, indicating that typhoid in humans is a …

Lipopolysaccharide O-antigens—bacterial glycans made to measure

C Whitfield, DM Williams, SD Kelly - Journal of Biological Chemistry, 2020 - ASBMB
Lipopolysaccharides are critical components of bacterial outer membranes. The more
conserved lipid A part of the lipopolysaccharide molecule is a major element in the …

Typhoidal Salmonella: Distinctive virulence factors and pathogenesis

R Johnson, E Mylona, G Frankel - Cellular microbiology, 2018 - Wiley Online Library
Although nontyphoidal Salmonella (NTS; including Salmonella Typhimurium) mainly cause
gastroenteritis, typhoidal serovars (Salmonella Typhi and Salmonella Paratyphi A) cause …

Salmonellae PhoPQ regulation of the outer membrane to resist innate immunity

ZD Dalebroux, SI Miller - Current opinion in microbiology, 2014 - Elsevier
Highlights•The Salmonellae PhoPQ virulence system is a major regulator of outer
membrane (OM) lipids and proteins.•Lipopolysaccharide (LPS) regulation increases …

Now you see me, now you don't: the interaction of Salmonella with innate immune receptors

AM Keestra-Gounder, RM Tsolis… - Nature Reviews …, 2015 - nature.com
Salmonella enterica serovars are associated with an estimated 1 million deaths annually
and are also useful model organisms for investigating the mechanisms of host–bacterium …

Comparative Analysis of Salmonella Genomes Identifies a Metabolic Network for Escalating Growth in the Inflamed Gut

SP Nuccio, AJ Bäumler - MBio, 2014 - Am Soc Microbiol
The Salmonella genus comprises a group of pathogens associated with illnesses ranging
from gastroenteritis to typhoid fever. We performed an in silico analysis of comparatively …

Examining the Link between Biofilm Formation and the Ability of Pathogenic Salmonella Strains to Colonize Multiple Host Species

KD MacKenzie, MB Palmer, WL Köster… - Frontiers in veterinary …, 2017 - frontiersin.org
Salmonella are important pathogens worldwide and a predominant number of human
infections are zoonotic in nature. The ability of strains to form biofilms, which is a …

The Pyromaniac Inside You: Salmonella Metabolism in the Host Gut

F Rivera-Chávez, AJ Bäumler - Annual review of microbiology, 2015 - annualreviews.org
A metabolically diverse microbial community occupies all available nutrient-niches in the
lumen of the mammalian intestine, making it difficult for pathogens to establish themselves in …

One species, different diseases: the unique molecular mechanisms that underlie the pathogenesis of typhoidal Salmonella infections

BX Wang, DSC Butler, M Hamblin… - Current opinion in …, 2023 - Elsevier
Highlights•Salmonella enterica is comprised of non-typhoidal and typhoidal
serovars.•Typhoidal Salmonella causes enteric fever instead of self-limiting …