Physical activity and exercise training have numerous health benefits, including the
prevention and management of chronic diseases, improvement of cardiovascular health …

Chronic moderate-intensity exercise is an efficient non-pharmacological strategy to prevent
and treat several diseases such as type 2 diabetes mellitus, cardiovascular and chronic …

Aims The present study verified the responses of selected endoplasmic reticulum (ER)
stress proteins (ie, BiP, ATF-6, pIRE1, pPERK, and peIF2alpha) in mice skeletal muscles …

Low body weight gain and food intake are related to exhaustive training and overtraining;
however, the molecular mechanisms responsible for these alterations remain unknown. The …

Background Regular physical activities have a positive effect on the muscular skeletal
system but overstrenuous exercise may be different. Transiently suppressed bone formation …

Inbred and genetically modified mice are frequently used to investigate the molecular
mechanisms responsible for the beneficial adaptations to exercise training. However …

The interest about circulating cell-free DNA (cfDNA) concentration increased from several
years because of its correlation with various conditions like osteoarthritis, cancers, stroke …

The aim of this study was to verify the effects of running overtraining protocols performed in
downhill, uphill, and without inclination on the proteins related to hypertrophy signaling …

In rheumatoid arthritis (RA), a chronic inflammatory disease, loss of muscle mass is an
important contributor to the loss of muscle strength in RA patients. Myostatin, a myokine …

In recent years, there has been increasing interest in the homeostatic response to extreme
exercises, especially in the integrated function of muscle and bone. The aim of this study …