Mitochondria are key intracellular organelles involved not only in the metabolic state of the
cell, but also in several cellular functions, such as proliferation, Calcium signaling, and lipid …

Recent advances have revealed common pathological changes in neurodegenerative
diseases, such as Alzheimer's disease, Parkinson's disease and amyotrophic lateral …

Mitochondria-associated endoplasmic reticulum membranes (MAMs) are dynamic
membrane coupling regions formed by the coupling of the mitochondrial outer membrane …

Hyperglycemia in diabetes mellitus (DM) patients is a causative factor for amyloidogenesis
and induces neuropathological changes, such as impaired neuronal integrity …

The mitochondria-associated membrane (MAM) has emerged as a cellular signaling hub
regulating various cellular processes. However, its molecular components remain unclear …

Membrane contact sites (MCS) between organelles of eukaryotic cells provide structural
integrity and promote organelle homeostasis by facilitating intracellular signaling, exchange …

Mitochondria-endoplasmic reticulum (ER) contact sites (MERCS) are morpho-functional
units, formed at the loci of close apposition of the ER-forming endomembrane and outer …

Autophagy is a process of intracellular self-recycling and degradation that plays an
important role in maintaining cell homeostasis. However, the molecular mechanism of …

Endoplasmic reticulum (ER)-mitochondria contact sites are crucial to allow Ca 2+ flux
between them and a plethora of proteins participate in tethering both organelles together …

Mitochondria and endoplasmic reticulum (ER) are fundamental in the control of cell
physiology regulating several signal transduction pathways. They continuously …