Hemoglobinopathies, including β-thalassemia and sickle cell disease (SCD), are common
genetic blood disorders. Endocrine disorders are frequent manifestations of organ damage …

In patients with TM, uncontrolled iron overload has serious clinical consequences with
considerable morbidity and mortality. Complications include liver damage, cardiac disease …

Pancreatic iron overload and diabetes mellitus (DM) are common in thalassemia major
patients. However, the relationship between iron stores and glucose disturbances is not well …

Introduction: Iron overload is a major problem in patients with b-thalassemia major, and it
has many structural and metabolic consequences. In this study, we aimed to consider the …

Beta thalassemia is the most common genetic blood disorder, characterized by reduced
production or complete absence of beta-globin chains. The combination of systematic red …

Thalassaemia is one of the most common genetic disorders caused by a reduction of the
globin chains leading to chronic haemolytic anaemia from birth. The mainstay of treatment is …

Iron overload in patients with thalassemia major (TM) affects glucose regulation and is
mediated by several mechanisms. The pathogenesis of glycaemic abnormalities in TM is …

β-Thalassemia major is a congenital hemoglobin disorder that requires regular blood
transfusion. The disease is often associated with iron overload and diabetes mellitus, among …

Background: This study aimed to investigate the prevalence of diabetes, impaired fasting
glucose (IFG) and impaired glucose tolerance (IGT) in Iranian patients with thalassemia …

Aim The present study was conducted to evaluate the frequency of Impaired Fasting
Glucose (IFG) and DM in TM patients in Southeast of Iran. Materials and Methods Fasting …