Familial Mediterranean fever: recent developments in pathogenesis and new recommendations for management

S Özen, ED Batu, S Demir - Frontiers in immunology, 2017 - frontiersin.org
Familial Mediterranean fever (FMF) is the most common monogenic autoinflammatory
disease (AID) affecting mainly the ethnic groups originating from Mediterranean basin. The …

Colchicine use in children and adolescents with familial Mediterranean fever: literature review and consensus statement

T Kallinich, D Haffner, T Niehues, K Huss, E Lainka… - …, 2007 - publications.aap.org
The daily application of colchicine is the standard therapy for prophylaxis of attacks and
amyloid deposition in familial Mediterranean fever. However, because of many issues (eg …

[HTML][HTML] EULAR recommendations for the management of familial Mediterranean fever

S Ozen, E Demirkaya, B Erer, A Livneh… - Annals of the …, 2016 - ard.bmj.com
Familial Mediterranean fever (FMF) is the most common monogenic autoinflammatory
disease, but many rheumatologists are not well acquainted with its management. The …

Familial mediterranean fever in Arabs

H El-Shanti, HA Majeed, M El-Khateeb - The Lancet, 2006 - thelancet.com
Autoinflammatory diseases are a group of disorders characterised by seemingly unprovoked
inflammation in the absence of high-titre autoantibodies or antigen-specific T cells, and …

Phenotype–genotype correlation in 91 patients with familial Mediterranean fever reveals a high frequency of cutaneomucous features

I Kone Paut, M Dubuc, J Sportouch, P Minodier… - …, 2000 - academic.oup.com
Objectives. To describe the clinical manifestations of familial Mediterranean fever (FMF) in
91 patients from 47 families and provide data from the genetic study. Patients and methods …

Development of the autoinflammatory disease damage index (ADDI)

NM Ter Haar, KV Annink, SM Al-Mayouf… - Annals of the …, 2017 - ard.bmj.com
Objectives Autoinflammatory diseases cause systemic inflammation that can result in
damage to multiple organs. A validated instrument is essential to quantify damage in …

The clinical patterns of myalgia in children with familial Mediterranean fever

HA Majeed, AK Al-Qudah, H Qubain… - Seminars in arthritis and …, 2000 - Elsevier
Objectives: To study the frequency and clinical patterns of myalgia in a defined group of
children with familial Mediterranean fever (FMF). Methods: A prospective 4-year (September …

Association of clinical and genetical features in FMF with focus on MEFV strip assay sensitivity in 452 children from western Anatolia, Turkey

C Ozturk, O Halıcıoglu, I Coker, N Gulez… - Clinical …, 2012 - Springer
The aim of this study was to determine the relationship between clinical findings and the
most common mutated alleles of MEFV gene in a childhood population and to determine the …

The spectrum of familial Mediterranean fever gene mutations in Arabs: report of a large series

HA Majeed, M El-Khateeb, H El-Shanti… - Seminars in arthritis and …, 2005 - Elsevier
OBJECTIVES: To identify the frequency and distribution of familial Mediterranean fever
(FMF) gene (MEFV) mutations in Arab patients. PATIENTS AND METHODS: The study was …

A narrative review on the role of cytokines in the pathogenesis and treatment of familial Mediterranean fever: an emphasis on pediatric cases

A Chaaban, H Yassine, R Hammoud, R Kanaan… - Frontiers in …, 2024 - frontiersin.org
Familial Mediterranean Fever (FMF) is a hereditary autoinflammatory disease characterized
by an early onset of recurrent fever and serositis episodes. FMF is caused by mutations in …