Biofilm lifestyle in recurrent urinary tract infections

ASA Lila, AAH Rajab, MH Abdallah, SMD Rizvi, A Moin… - Life, 2023 - mdpi.com
Urinary tract infections (UTIs) represent one of the most common infections that are
frequently encountered in health care facilities. One of the main mechanisms used by …

[HTML][HTML] What's old is new again: Insights into diabetic foot microbiome

AAH Rajab, WAH Hegazy - World Journal of Diabetes, 2023 - ncbi.nlm.nih.gov
Diabetes is a chronic disease that is considered one of the most stubborn global health
problems that continues to defy the efforts of scientists and physicians. The prevalence of …

Characterization of the anti-biofilm and anti-quorum sensing activities of the β-adrenoreceptor antagonist atenolol against gram-negative bacterial pathogens

S Cavalu, SS Elbaramawi, AG Eissa… - International Journal of …, 2022 - mdpi.com
The development of bacterial resistance to antibiotics is an increasing public health issue
that worsens with the formation of biofilms. Quorum sensing (QS) orchestrates the bacterial …

Anti-Quorum Sensing Activities of Gliptins against Pseudomonas aeruginosa and Staphylococcus aureus

MT Khayat, HA Abbas, TS Ibrahim, AN Khayyat… - Biomedicines, 2022 - mdpi.com
The development of bacterial resistance to traditional antibiotics constitutes an emerging
public health issue. Promising approaches have been innovated to conquer bacterial …

Terazosin Interferes with Quorum Sensing and Type Three Secretion System and Diminishes the Bacterial Espionage to Mitigate the Salmonella Typhimurium …

WAH Hegazy, IM Salem, HF Alotaibi, ES Khafagy… - Antibiotics, 2022 - mdpi.com
Salmonella enterica is an invasive intracellular pathogen and hires diverse systems to
manipulate its survival in the host cells. Salmonella could eavesdrop on the host cells …

Drug repositioning: doxazosin attenuates the virulence factors and biofilm formation in Gram-negative bacteria

MA Elfaky, SS Elbaramawi, AG Eissa… - Applied Microbiology …, 2023 - Springer
The resistance development is an increasing global health risk that needs innovative
solutions. Repurposing drugs to serve as anti-virulence agents is suggested as an …

Diminishing the Pathogenesis of the Food-Borne Pathogen Serratia marcescens by Low Doses of Sodium Citrate

MT Khayat, SS Elbaramawi, SI Nazeih, MK Safo… - Biology, 2023 - mdpi.com
Simple Summary Sodium citrate is a safe and frequently used food additive; the objective of
this study is to assess the effectiveness of sodium citrate at low concentrations of 4% or 5 …

Silencing of Salmonella typhimurium Pathogenesis: Atenolol Acquires Efficient Anti-Virulence Activities

AK Thabit, K Eljaaly, A Zawawi, TS Ibrahim, AG Eissa… - Microorganisms, 2022 - mdpi.com
The targeting of bacterial virulence is proposed as a promising approach to overcoming the
bacterial resistance development to antibiotics. Salmonella enterica is one of the most …

Muting bacterial communication: evaluation of prazosin anti-quorum sensing activities against gram-negative bacteria Pseudomonas aeruginosa, Proteus mirabilis …

AK Thabit, K Eljaaly, A Zawawi, TS Ibrahim, AG Eissa… - Biology, 2022 - mdpi.com
Simple Summary Bacterial infections are considered one of the main challenges to global
health. Bacterial virulence is controlled by interplayed systems to regulate bacterial invasion …

Amphotericin B-PEG conjugates of ZnO nanoparticles: enhancement antifungal activity with minimal toxicity

SM Alshahrani, ES Khafagy, Y Riadi, A Al Saqr… - Pharmaceutics, 2022 - mdpi.com
Amphotericin B (AMB) is commonly used to treat life-threatening systemic fungal infections.
AMB formulations that are more efficient and less nephrotoxic are currently unmet needs. In …