Long non-coding RNAs: definitions, functions, challenges and recommendations
Genes specifying long non-coding RNAs (lncRNAs) occupy a large fraction of the genomes
of complex organisms. The term 'lncRNAs' encompasses RNA polymerase I (Pol I), Pol II …
of complex organisms. The term 'lncRNAs' encompasses RNA polymerase I (Pol I), Pol II …
The state of long non-coding RNA biology
JS Mattick - Non-coding RNA, 2018 - mdpi.com
Transcriptomic studies have demonstrated that the vast majority of the genomes of mammals
and other complex organisms is expressed in highly dynamic and cell-specific patterns to …
and other complex organisms is expressed in highly dynamic and cell-specific patterns to …
Measuring performance metrics of machine learning algorithms for detecting and classifying transposable elements
S Orozco-Arias, JS Piña, R Tabares-Soto… - Processes, 2020 - mdpi.com
Because of the promising results obtained by machine learning (ML) approaches in several
fields, every day is more common, the utilization of ML to solve problems in bioinformatics. In …
fields, every day is more common, the utilization of ML to solve problems in bioinformatics. In …
[HTML][HTML] Lamarck and Panspermia-On the efficient spread of living systems throughout the cosmos
EJ Steele, RM Gorczynski, RA Lindley, Y Liu… - Progress in Biophysics …, 2019 - Elsevier
We review the main lines of evidence (molecular, cellular and whole organism) published
since the 1970s demonstrating Lamarckian Inheritance in animals, plants and …
since the 1970s demonstrating Lamarckian Inheritance in animals, plants and …
A systematic review of the application of machine learning in the detection and classification of transposable elements
Background Transposable elements (TEs) constitute the most common repeated sequences
in eukaryotic genomes. Recent studies demonstrated their deep impact on species diversity …
in eukaryotic genomes. Recent studies demonstrated their deep impact on species diversity …
Structure-based screening for functional non-coding RNAs in fission yeast identifies a factor repressing untimely initiation of sexual differentiation
Y Ono, K Katayama, T Onuma, K Kubo… - Nucleic acids …, 2022 - academic.oup.com
Non-coding RNAs (ncRNAs) ubiquitously exist in normal and cancer cells. Despite their
prevalent distribution, the functions of most long ncRNAs remain uncharacterized. The …
prevalent distribution, the functions of most long ncRNAs remain uncharacterized. The …
A proposed reverse transcription mechanism for (CAG) n and similar expandable repeats that cause neurological and other diseases
A Franklin, EJ Steele, RA Lindley - Heliyon, 2020 - cell.com
The mechanism of (CAG) n repeat generation, and related expandable repeat diseases in
non-dividing cells, is currently understood in terms of a DNA template-based DNA repair …
non-dividing cells, is currently understood in terms of a DNA template-based DNA repair …
Deep forest ensemble learning for classification of alignments of non-coding RNA sequences based on multi-view structure representations
Non-coding RNAs (ncRNAs) play crucial roles in multiple biological processes. However,
only a few ncRNAs' functions have been well studied. Given the significance of ncRNAs …
only a few ncRNAs' functions have been well studied. Given the significance of ncRNAs …
[PDF][PDF] Clusters of mammalian conserved RNA structures in UTRs associate with RBP binding sites
VP Gadekar, AW Munk, M Miladi… - NAR Genomics and …, 2024 - academic.oup.com
RNA secondary structures play essential roles in the formation of the tertiary structure and
function of a transcript. Recent genome-wide studies highlight significant potential for RNA …
function of a transcript. Recent genome-wide studies highlight significant potential for RNA …