[HTML][HTML] The biology of cancer testis antigens: putative function, regulation and therapeutic potential
E Fratta, S Coral, A Covre, G Parisi, F Colizzi… - Molecular …, 2011 - Elsevier
Cancer testis antigens (CTA) are a large family of tumor-associated antigens expressed in
human tumors of different histological origin, but not in normal tissues except for testis and …
human tumors of different histological origin, but not in normal tissues except for testis and …
Cancer/testis‐associated genes: identification, expression profile, and putative function
AJW Zendman, DJ Ruiter… - Journal of cellular …, 2003 - Wiley Online Library
Cancer/testis‐associated genes (CTAs) are a subgroup of tumor antigens with a restricted
expression in testis and malignancies. During the last decade, many of these …
expression in testis and malignancies. During the last decade, many of these …
Overexpression of MAGE/GAGE Genes in Paclitaxel/Doxorubicin-resistant Human Cancer Cell Lines
Z Duan, Y Duan, DE Lamendola, RZ Yusuf… - Clinical cancer …, 2003 - AACR
Previous studies directed at identifying paclitaxel resistance genes in a paclitaxel-resistant
subclone of the human ovarian cancer cell line SKOV-3 identified a novel cancer testis …
subclone of the human ovarian cancer cell line SKOV-3 identified a novel cancer testis …
Phase I study of decitabine-mediated gene expression in patients with cancers involving the lungs, esophagus, or pleura
DS Schrump, MR Fischette, DM Nguyen, M Zhao… - Clinical Cancer …, 2006 - AACR
Purpose: The DNA methylation paradox, manifested as derepression of cancer-testis
antigens, and silencing of tumor suppressors during malignant transformation, provides the …
antigens, and silencing of tumor suppressors during malignant transformation, provides the …
Promoter Demethylation and Histone Acetylation Mediate Gene Expression of MAGE-A1, -A2, -A3, and -A12 in Human Cancer Cells
F Wischnewski, K Pantel, H Schwarzenbach - Molecular Cancer Research, 2006 - AACR
The broad range of expression of cancer-testis antigens in various tumor types makes the
proteins encoded by human MAGE gene family promising targets for anticancer …
proteins encoded by human MAGE gene family promising targets for anticancer …
Fragmentation-based methods and systems for sequence variation detection and discovery
D Van Den Boom, S Boecker - US Patent 7,820,378, 2010 - Google Patents
US7820378B2 - Fragmentation-based methods and systems for sequence variation detection
and discovery - Google Patents US7820378B2 - Fragmentation-based methods and systems …
and discovery - Google Patents US7820378B2 - Fragmentation-based methods and systems …
An epigenome-wide association study of sex-specific chronological ageing
Background Advanced age is associated with cognitive and physical decline and is a major
risk factor for a multitude of disorders. There is also a gap in life expectancy between males …
risk factor for a multitude of disorders. There is also a gap in life expectancy between males …
Treatment of ovarian cancer cell lines with 5-aza-2′-deoxycytidine upregulates the expression of cancer-testis antigens and class I major histocompatibility complex …
SJ Adair, KT Hogan - Cancer immunology, immunotherapy, 2009 - Springer
Purpose To test the hypothesis that decrease in DNA methylation will increase the
expression of cancer-testis antigens (CTA) and class I major histocompatibility complex …
expression of cancer-testis antigens (CTA) and class I major histocompatibility complex …
DNA methyltransferase inhibitors: catalysts for antitumour immune responses
H Dan, S Zhang, Y Zhou, Q Guan - OncoTargets and therapy, 2019 - Taylor & Francis
Epigenetics is a kind of heritable change that involves the unaltered DNA sequence and can
have effects on gene expression. The regulatory mechanism mainly includes DNA …
have effects on gene expression. The regulatory mechanism mainly includes DNA …
Co-occurring Mutations of Tumor Suppressor Genes, LATS2 and NF2, in Malignant Pleural Mesothelioma
R Tranchant, L Quetel, A Tallet, C Meiller, A Renier… - Clinical Cancer …, 2017 - AACR
Purpose: To better define malignant pleural mesothelioma (MPM) heterogeneity and identify
molecular subtypes of MPM, we focus on the tumor suppressor gene LATS2, a member of …
molecular subtypes of MPM, we focus on the tumor suppressor gene LATS2, a member of …