Despite a continuing debate about the existence of cancer stem cells (CSCs), recent
discoveries have provided further support for their existence and their roles in drug …

Osteosarcoma (OS) is a class of cancer originating from bone, mainly afflicting children or
young adults. It is the second highest cause of cancer-related death in these age groups …

Machine learning is a branch of artificial intelligence that employs a variety of statistical,
probabilistic and optimization techniques that allows computers to “learn” from past …

Metastatic dissemination is the leading cause of death in cancer patients, which is
particularly evident for high-risk sarcomas such as Ewing sarcoma, osteosarcoma, and …

Purpose: High-grade osteosarcoma is a malignant primary bone tumor with a peak
incidence in adolescence. Overall survival (OS) of patients with resectable metastatic …

Background Tumor cell invasion into adjacent normal brain is a mesenchymal feature of
GBM and a major factor contributing to their dismal outcomes. Therefore, better …

Background Pulmonary metastasis continues to be the most common cause of death in
osteosarcoma. Indeed, the 5-year survival for newly diagnosed osteosarcoma patients has …

Osteosarcoma is the most common primary malignancy of bone, typically presenting in the
first or second decade of life. Unfortunately, clinical outcomes for osteosarcoma patients …

Endometrial cancer (EC) is a prevalent uterine cancer that remains a major contributor to
cancer-associated morbidity and mortality. EC diagnosed at advanced stages shows a poor …

At present, patients with nonmetastatic osteosarcoma of the extremity aged less than 40
years have an expected 5-year survival rate of 70% with a chemotherapy regimen based on …