Human health during space travel: state-of-the-art review
C Krittanawong, NK Singh, RA Scheuring, E Urquieta… - Cells, 2022 - mdpi.com
The field of human space travel is in the midst of a dramatic revolution. Upcoming missions
are looking to push the boundaries of space travel, with plans to travel for longer distances …
are looking to push the boundaries of space travel, with plans to travel for longer distances …
Secondary immunodeficiencies: an overview
KS Tuano, N Seth, J Chinen - Annals of Allergy, Asthma & Immunology, 2021 - Elsevier
Objective To review the different causes of secondary immunodeficiencies and provide
clinicians with an updated overview of potential factors that contribute to immunodeficiency …
clinicians with an updated overview of potential factors that contribute to immunodeficiency …
Single-cell analysis identifies conserved features of immune dysfunction in simulated microgravity and spaceflight
Microgravity is associated with immunological dysfunction, though the mechanisms are
poorly understood. Here, using single-cell analysis of human peripheral blood mononuclear …
poorly understood. Here, using single-cell analysis of human peripheral blood mononuclear …
Exercise as a countermeasure for latent viral reactivation during long duration space flight
NH Agha, SK Mehta, BV Rooney… - The FASEB …, 2020 - Wiley Online Library
Latent viral reactivation is a commonly reported manifestation of immune system
dysregulation during spaceflight. As physical fitness and exercise training have been shown …
dysregulation during spaceflight. As physical fitness and exercise training have been shown …
Gut microbiome and space travelers' health: state of the art and possible pro/prebiotic strategies for long-term space missions
The upcoming exploration missions will imply a much longer duration than any of the
missions flown so far. In these missions, physiological adaptation to the new environment …
missions flown so far. In these missions, physiological adaptation to the new environment …
Secretome profiling reveals acute changes in oxidative stress, brain homeostasis, and coagulation following short-duration spaceflight
As spaceflight becomes more common with commercial crews, blood-based measures of
crew health can guide both astronaut biomedicine and countermeasures. By profiling …
crew health can guide both astronaut biomedicine and countermeasures. By profiling …
Key points for the development of antioxidant cocktails to prevent cellular stress and damage caused by reactive oxygen species (ROS) during manned space …
X Gómez, S Sanon, K Zambrano, S Asquel… - npj …, 2021 - nature.com
Exposure to microgravity and ionizing radiation during spaceflight missions causes
excessive reactive oxygen species (ROS) production that contributes to cellular stress and …
excessive reactive oxygen species (ROS) production that contributes to cellular stress and …
The future of personalized medicine in space: from observations to countermeasures
E Pavez Loriè, S Baatout, A Choukér… - … in bioengineering and …, 2021 - frontiersin.org
The aim of personalized medicine is to detach from a “one-size fits all approach” and
improve patient health by individualization to achieve the best outcomes in disease …
improve patient health by individualization to achieve the best outcomes in disease …
How does spaceflight affect the acquired immune system?
The impact of spaceflight on the immune system has been investigated extensively during
spaceflight missions and in model experiments conducted on Earth. Data suggest that the …
spaceflight missions and in model experiments conducted on Earth. Data suggest that the …
Overview of lunar dust toxicity risk
M Pohlen, D Carroll, GK Prisk, AJ Sawyer - npj Microgravity, 2022 - nature.com
Lunar dust (LD), the component of lunar regolith with particle sizes less than 20 μm, covers
the surface of the Moon. Due to its fineness, jagged edges, and electrostatic charge, LD …
the surface of the Moon. Due to its fineness, jagged edges, and electrostatic charge, LD …