Neuroinflammation in HIV-associated depression: Evidence and future perspectives
People living with HIV face a high risk of mental illness, especially depression. We do not yet
know the precise neurobiological mechanisms underlying HIV-associated depression …
know the precise neurobiological mechanisms underlying HIV-associated depression …
Dopamine receptors: is it possible to become a therapeutic target for depression?
F Zhao, Z Cheng, J Piao, R Cui, B Li - Frontiers in Pharmacology, 2022 - frontiersin.org
Dopamine and its receptors are currently recognized targets for the treatment of several
neuropsychiatric disorders, including Parkinson's disease, schizophrenia, some drug use …
neuropsychiatric disorders, including Parkinson's disease, schizophrenia, some drug use …
Compartmentalization of cerebrospinal fluid inflammation across the spectrum of untreated HIV-1 infection, central nervous system injury and viral suppression
Objective To characterize the evolution of central nervous system (CNS) inflammation in HIV-
1 infection applying a panel of cerebrospinal fluid (CSF) inflammatory biomarkers to …
1 infection applying a panel of cerebrospinal fluid (CSF) inflammatory biomarkers to …
HIV-associated apathy/depression and neurocognitive impairments reflect persistent dopamine deficits
KA McLaurin, M Harris, V Madormo, SB Harrod… - Cells, 2021 - mdpi.com
Individuals living with human immunodeficiency virus type 1 (HIV-1) are often plagued by
debilitating neurocognitive impairments and affective alterations; the pathophysiology …
debilitating neurocognitive impairments and affective alterations; the pathophysiology …
[HTML][HTML] Biomarkers of central and peripheral inflammation mediate the association between HIV and depressive symptoms
People living with HIV are at increased risk for depression, though the underlying
mechanisms for this are unclear. In the general population, depression is associated with …
mechanisms for this are unclear. In the general population, depression is associated with …
Global systematic review of common mental health disorders in adults living with HIV
J Hoare, T Sevenoaks, B Mtukushe, T Williams… - Current HIV/AIDS …, 2021 - Springer
Purpose of the review By reviewing the most recent common mental health disorders
(CMHD) studies in people living with HIV (PLWH)(2018-2020), this review discusses the …
(CMHD) studies in people living with HIV (PLWH)(2018-2020), this review discusses the …
The comorbidity of depression and neurocognitive disorder in persons with HIV infection: call for investigation and treatment
K Goodkin, TH Evering, AM Anderson… - Frontiers in Cellular …, 2023 - frontiersin.org
Depression and neurocognitive disorder continue to be the major neuropsychiatric disorders
affecting persons with HIV (PWH). The prevalence of major depressive disorder is two to …
affecting persons with HIV (PWH). The prevalence of major depressive disorder is two to …
Bidirectional relationship between HIV/HBV infection and comorbid depression and/or anxiety: a systematic review on shared biological mechanisms
M Fabrazzo, S Cipolla, M Pisaturo… - Journal of personalized …, 2023 - mdpi.com
Background: Mental disorders that are comorbid with chronic infectious diseases may
worsen clinical outcomes and patients' quality of life. We hypothesized that depression …
worsen clinical outcomes and patients' quality of life. We hypothesized that depression …
Changes in cerebrospinal fluid proteins across the spectrum of untreated and treated chronic HIV-1 infection
Z Hu, P Cinque, A Dravid, L Hagberg, A Yilmaz… - PLoS …, 2024 - journals.plos.org
Using the Olink Explore 1536 platform, we measured 1,463 unique proteins in 303
cerebrospinal fluid (CSF) specimens from four clinical centers contributed by uninfected …
cerebrospinal fluid (CSF) specimens from four clinical centers contributed by uninfected …
Biomarkers of central and peripheral inflammation mediate the association between HIV and depressive symptoms
People living with HIV are at increased risk for depression, though the underlying
mechanisms for this are unclear. In the general population, depression is associated with …
mechanisms for this are unclear. In the general population, depression is associated with …