SA Durward-Akhurst… - … Clinics: Equine Practice, 2025 - vetequine.theclinics.com
Inflammatory myopathies are a heterogenous group of muscle disorders characterized by infiltration of leukocytes into skeletal muscle and around blood vessels. 1–3 Neutrophils …
In horses, immune-mediated muscle disorders can arise from an overzealous immune response to concurrent infections or potentially from an inherent immune response to host …
Myosinopathies are defined as a group of muscle disorders characterized by mutations in genes encoding myosin heavy chains. Their exact molecular and cellular mechanisms …
CJ Finno, G Gianino, S Perumbakkam, ZJ Williams… - Skeletal muscle, 2018 - Springer
Background The cause of immune-mediated myositis (IMM), characterized by recurrent, rapid-onset muscle atrophy in Quarter Horses (QH), is unknown. The histopathologic …
SJ Valberg, ML Henry, S Perumbakkam… - Journal of veterinary …, 2018 - Wiley Online Library
Background An E321G mutation in MYH1 was recently identified in Quarter Horses (QH) with immune‐mediated myositis (IMM) defined by a phenotype of gross muscle atrophy and …
Background Immune‐mediated myositis (IMM) in American Quarter Horses (QHs) causes acute muscle atrophy and lymphocytic infiltration of myofibers. Recently, an E321G mutation …
Horses affected by chronic piroplasmosis may develop poor performance and muscle atrophy. Here we investigate the pathological and immunopathological aspects of myopathy …
L Hunyadi, EA Sundman, PH Kass… - Journal of veterinary …, 2017 - Wiley Online Library
Background Immune‐mediated myositis (IMM) is a cause of rhabdomyolysis, stiffness, and muscle atrophy predominantly affecting Quarter horses. Limited information is available with …
AL de Albuquerque, DJ Zanzarini Delfiol… - Equine Veterinary …, 2022 - Wiley Online Library
Summary Background In the Quarter Horse (QH), myosin heavy chain myopathy (MYHM), which is characterised by nonexertional rhabdomyolysis or immune‐mediated myositis …