Streptococcus equi Infections in Horses: Guidelines for Treatment, Control, and Prevention of Strangles—Revised Consensus Statement

AG Boyle, JF Timoney, JR Newton… - Journal of Veterinary …, 2018 - Wiley Online Library
This consensus statement update reflects our current published knowledge and opinion
about clinical signs, pathogenesis, epidemiology, treatment, complications, and control of …

Myosin Heavy Chain Myopathy and Immune-Mediated Muscular Disorders

SA Durward-Akhurst… - … Clinics: Equine Practice, 2025 - vetequine.theclinics.com
Inflammatory myopathies are a heterogenous group of muscle disorders characterized by
infiltration of leukocytes into skeletal muscle and around blood vessels. 1–3 Neutrophils …

Immune-mediated muscle diseases of the horse

SA Durward-Akhurst, SJ Valberg - Veterinary pathology, 2018 - journals.sagepub.com
In horses, immune-mediated muscle disorders can arise from an overzealous immune
response to concurrent infections or potentially from an inherent immune response to host …

Myofibre Hyper-Contractility in Horses Expressing the Myosin Heavy Chain Myopathy Mutation, MYH1E321G

J Ochala, CJ Finno, SJ Valberg - Cells, 2021 - mdpi.com
Myosinopathies are defined as a group of muscle disorders characterized by mutations in
genes encoding myosin heavy chains. Their exact molecular and cellular mechanisms …

A missense mutation in MYH1 is associated with susceptibility to immune-mediated myositis in Quarter Horses

CJ Finno, G Gianino, S Perumbakkam, ZJ Williams… - Skeletal muscle, 2018 - Springer
Background The cause of immune-mediated myositis (IMM), characterized by recurrent,
rapid-onset muscle atrophy in Quarter Horses (QH), is unknown. The histopathologic …

An E321G MYH1 mutation is strongly associated with nonexertional rhabdomyolysis in Quarter Horses

SJ Valberg, ML Henry, S Perumbakkam… - Journal of veterinary …, 2018 - Wiley Online Library
Background An E321G mutation in MYH1 was recently identified in Quarter Horses (QH)
with immune‐mediated myositis (IMM) defined by a phenotype of gross muscle atrophy and …

Prevalence of the E321G MYH1 variant for immune‐mediated myositis and nonexertional rhabdomyolysis in performance subgroups of American Quarter Horses

GM Gianino, SJ Valberg… - Journal of veterinary …, 2019 - Wiley Online Library
Background Immune‐mediated myositis (IMM) in American Quarter Horses (QHs) causes
acute muscle atrophy and lymphocytic infiltration of myofibers. Recently, an E321G mutation …

Inflammatory myopathy in horses with chronic piroplasmosis

MP Pasolini, TB Pagano, A Costagliola… - Veterinary …, 2018 - journals.sagepub.com
Horses affected by chronic piroplasmosis may develop poor performance and muscle
atrophy. Here we investigate the pathological and immunopathological aspects of myopathy …

Clinical implications and hospital outcome of immune‐mediated myositis in horses

L Hunyadi, EA Sundman, PH Kass… - Journal of veterinary …, 2017 - Wiley Online Library
Background Immune‐mediated myositis (IMM) is a cause of rhabdomyolysis, stiffness, and
muscle atrophy predominantly affecting Quarter horses. Limited information is available with …

Prevalence of the E321G MYH1 variant in Brazilian Quarter Horses

AL de Albuquerque, DJ Zanzarini Delfiol… - Equine Veterinary …, 2022 - Wiley Online Library
Summary Background In the Quarter Horse (QH), myosin heavy chain myopathy (MYHM),
which is characterised by nonexertional rhabdomyolysis or immune‐mediated myositis …