Current uses and resistance mechanisms of enzalutamide in prostate cancer treatment
CD Miller, P Likasitwatanakul, E Toye… - Expert Review of …, 2024 - Taylor & Francis
Introduction Prostate cancer continues to be a major cause of morbidity and mortality for
men worldwide. Enzalutamide, a second-generation non-steroidal antiandrogen that blocks …
men worldwide. Enzalutamide, a second-generation non-steroidal antiandrogen that blocks …
Stromal-derived MAOB promotes prostate cancer growth and progression
Prostate cancer (PC) develops in a microenvironment where the stromal cells modulate
adjacent tumor growth and progression. Here, we demonstrated elevated levels of …
adjacent tumor growth and progression. Here, we demonstrated elevated levels of …
[HTML][HTML] Cholinergic signaling via muscarinic M1 receptor confers resistance to docetaxel in prostate cancer
Docetaxel is the most commonly used chemotherapy for advanced prostate cancer (PC),
including castration-resistant disease (CRPC), but the eventual development of docetaxel …
including castration-resistant disease (CRPC), but the eventual development of docetaxel …
PlexinD1 is a driver and a therapeutic target in advanced prostate cancer
Aggressive prostate cancer (PCa) variants associated with androgen receptor signaling
inhibitor (ARSI) resistance and metastasis remain poorly understood. Here, we identify the …
inhibitor (ARSI) resistance and metastasis remain poorly understood. Here, we identify the …
Plexin D1 emerges as a novel target in the development of neural lineage plasticity in treatment-resistant prostate cancer
Abstract Treatment-induced neuroendocrine prostate cancer (t-NEPC) often arises from
adenocarcinoma via lineage plasticity in response to androgen receptor signaling inhibitors …
adenocarcinoma via lineage plasticity in response to androgen receptor signaling inhibitors …
Unraveling the Peripheral Nervous System's Role in Tumor: A Double-edged Sword
YH Wang, X Yang, CC Liu, X Wang, KD Yu - Cancer Letters, 2025 - Elsevier
The peripheral nervous system (PNS) includes all nerves outside the brain and spinal cord,
comprising various cells like neurons and glial cells, such as schwann and satellite cells …
comprising various cells like neurons and glial cells, such as schwann and satellite cells …
[HTML][HTML] Plexin D1 emerges as a novel target in the development of neural lineage plasticity in treatment-resistant prostate cancer
Abstract Treatment-induced neuroendocrine prostate cancer (t-NEPC) often arises from
adenocarcinoma via lineage plasticity in response to androgen receptor signaling inhibitors …
adenocarcinoma via lineage plasticity in response to androgen receptor signaling inhibitors …
Identifying Efficacious Therapies for High Glycolysis Metastatic Castration-Resistant Prostate Cancer
MC Su - 2024 - search.proquest.com
Metastatic castration-resistant prostate cancer (mCRPC) remains a deadly disease due to a
lack of efficacious treatments. The reprogramming of cancer metabolism toward elevated …
lack of efficacious treatments. The reprogramming of cancer metabolism toward elevated …