Evaluating the virology and evolution of seasonal human coronaviruses associated with the common cold in the COVID-19 era

CM Harrison, JM Doster, EH Landwehr, NP Kumar… - Microorganisms, 2023 - mdpi.com
Approximately 15–30% of all cases of the common cold are due to human coronavirus
infections. More recently, the emergence of the more severe respiratory coronaviruses …

Roles of RNA sensors in host innate response to influenza virus and coronavirus infections

W Li, H Wang, SJ Zheng - International Journal of Molecular Sciences, 2022 - mdpi.com
Influenza virus and coronavirus are two important respiratory viruses, which often cause
serious respiratory diseases in humans and animals after infection. In recent years, highly …

Manipulation of innate immune signaling pathways by SARS-CoV-2 non-structural proteins

Y Lu, HA Michel, PH Wang, GL Smith - Frontiers in Microbiology, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the
current coronavirus disease 2019 (COVID-19) pandemic, induces an unbalanced immune …

Allosteric activation of SARS-CoV-2 RNA-dependent RNA polymerase by remdesivir triphosphate and other phosphorylated nucleotides

B Wang, V Svetlov, YI Wolf, EV Koonin, E Nudler… - MBio, 2021 - Am Soc Microbiol
The catalytic subunit of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
RNA-dependent RNA polymerase (RdRp) Nsp12 has a unique nidovirus RdRp-associated …

Plasma proteome fingerprints reveal distinctiveness and clinical outcome of SARS-CoV-2 infection

W Bauer, M Weber, E Diehl-Wiesenecker, N Galtung… - Viruses, 2021 - mdpi.com
Background: We evaluated how plasma proteomic signatures in patients with suspected
COVID-19 can unravel the pathophysiology, and determine kinetics and clinical outcome of …

[HTML][HTML] Cold atmospheric plasma: A non-negligible strategy for viral RNA inactivation to prevent SARS-CoV-2 environmental transmission

T Jin, Y Xu, C Dai, X Zhou, Q Xu, Z Wu - Aip Advances, 2021 - pubs.aip.org
Cold atmospheric plasma (CAP), regarded as a powerful physics technology, displays
antimicrobial, antitumor, and even antiviral properties, but the underlying mechanism is …

MERS-CoV-nsp5 expression in human epithelial BEAS 2b cells attenuates type I interferon production by inhibiting IRF3 nuclear translocation

Y Zhang, S Kandwal, D Fayne… - Cellular and Molecular Life …, 2024 - Springer
Abstract Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is an enveloped,
positive-sense RNA virus that emerged in 2012, causing sporadic cases and localized …

Inhibition of the IFN-α JAK/STAT pathway by MERS-CoV and SARS-CoV-1 proteins in human epithelial cells

Y Zhang, S Gargan, FM Roche, M Frieman… - Viruses, 2022 - mdpi.com
Coronaviruses (CoVs) have caused several global outbreaks with relatively high mortality
rates, including Middle East Respiratory Syndrome coronavirus (MERS)-CoV, which …

The evolutionary dance between innate host antiviral pathways and SARS-CoV-2

SR Aliyari, N Quanquin, O Pernet, S Zhang, L Wang… - Pathogens, 2022 - mdpi.com
Compared to what we knew at the start of the SARS-CoV-2 global pandemic, our
understanding of the interplay between the interferon signaling pathway and SARS-CoV-2 …

An Evaluation of Type 1 Interferon Related Genes in Male and Female-Matched, SARS-CoV-2 Infected Individuals Early in the COVID-19 Pandemic

TP Huecksteadt, EJ Myers, SE Aamodt, S Trivedi… - Viruses, 2024 - mdpi.com
SARS-CoV-2 infection has claimed just over 1.1 million lives in the US since 2020. Globally,
the SARS-CoV-2 respiratory infection spread to 771 million people and caused mortality in …