The discovery that brain tissue could potentially be salvaged from ischaemia due to stroke,
has led to major advances in the development of therapies for ischemic stroke. In this …

We review the hemodynamic, metabolic and cellular parameters affected during early
ischemia and their changes as a function of approximate cerebral blood flow (CBF) …

Variations in oxygen levels play key roles in numerous physiological and pathological
processes, but are often not properly controlled in in vitro models, introducing a significant …

Original experimental studies in nonhuman primate models of focal ischemia showed flow-
related changes in evoked potentials that suggested a circumferential zone of low regional …

In the past decade, researchers have been immensely focused on nanotechnology and
profoundly efforts to investigate the electrical, optical and magnetic properties of …

Background and Purpose—Nitroimidazole imaging is a promising contender for noninvasive
in vivo mapping of brain hypoxia after stroke. However, there is a dearth of knowledge about …

Oxygen utilization is central to the human brain's high metabolic rate. Measurement of this
fundamental process, in both disease and health, has been a focus of research attention …

Positron emission tomography (PET) is widely used in clinical and animal studies, along
with the development of diverse tracers. The biochemical characteristics of PET tracers may …

The aim of thrombolytic therapy after acute ischemic stroke is salvage of the ischemic
penumbra. Several imaging techniques have been used to identify the penumbra in patients …

Abstract 'True'transient ischaemic attacks are characterized not only clinically, but also
radiologically by a lack of corresponding changes on magnetic resonance imaging. During a …