European evidence-based consensus on the diagnosis and management of ulcerative colitis: definitions and diagnosis

EF Stange, SPL Travis, S Vermeire… - Journal of Crohn's …, 2008 - academic.oup.com
Ulcerative colitis is a life long disease arising from an interaction between genetic and
environmental factors, but observed predominantly in the developed countries of the world …

Extraintestinal manifestations of inflammatory bowel disease

S Ardizzone, PS Puttini, A Cassinotti… - Digestive and liver disease, 2008 - Elsevier
Inflammatory bowel disease (IBD) is associated with a variety of extraintestinal
manifestations (EIMs) that may produce greater morbidity than the underlying intestinal …

Management of paediatric ulcerative colitis, part 1: ambulatory care—an evidence-based guideline from European Crohn's and Colitis Organization and European …

D Turner, FM Ruemmele… - Journal of pediatric …, 2018 - journals.lww.com
Background: The contemporary management of ambulatory ulcerative colitis (UC) continues
to be challenging with∼ 20% of children needing a colectomy within childhood years. We …

Management of pediatric ulcerative colitis: joint ECCO and ESPGHAN evidence-based consensus guidelines

D Turner, A Levine, JC Escher… - Journal of pediatric …, 2012 - journals.lww.com
Methods: A group of 27 experts in pediatric IBD participated in an iterative consensus
process including 2 face-to-face meetings, following an open call to ESPGHAN and ECCO …

European evidence-based consensus on the management of ulcerative colitis: special situations

L Biancone, P Michetti, S Travis… - Journal of Crohn's …, 2008 - academic.oup.com
About 10–15% of patients with inflammatory bowel disease are diagnosed before the age of
18 years. 121 During puberty the incidence is 7 per 100 000 per year and increases further …

Approach to a patient with elevated serum alkaline phosphatase

A Siddique, KV Kowdley - Clinics in liver disease, 2012 - liver.theclinics.com
The term cholestasis is derived from the Greek word “chole,” which means bile, and “stasis,”
meaning standing still. Cholestasis develops either from a defect in bile synthesis …

Meta-analysis reveals an association of PTPN22 C1858T with autoimmune diseases, which depends on the localization of the affected tissue

J Zheng, S Ibrahim, F Petersen, X Yu - Genes & Immunity, 2012 - nature.com
Protein tyrosine phosphatase non-receptor type 22 (PTPN22) is a strong susceptibility gene
shared by many autoimmune diseases. The aim of this study was to explore the …

Hyaluronan in immune dysregulation and autoimmune diseases

N Nagy, HF Kuipers, PL Marshall, E Wang, G Kaber… - Matrix Biology, 2019 - Elsevier
The tissue microenvironment contributes to local immunity and to the pathogenesis of
autoimmune diseases-a diverse set of conditions characterized by sterile inflammation …

[HTML][HTML] CCL24 regulates biliary inflammation and fibrosis in primary sclerosing cholangitis

R Greenman, M Segal-Salto, N Barashi, O Hay… - JCI insight, 2023 - ncbi.nlm.nih.gov
Abstract ˆCCL24 is a pro-fibrotic, pro-inflammatory chemokine expressed in several chronic
fibrotic diseases. In the liver, CCL24 plays a role in fibrosis and inflammation, and blocking …

Primary sclerosing cholangitis

MG Silveira, KD Lindor - Canadian Journal of Gastroenterology …, 2008 - Wiley Online Library
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease characterized by
inflammation and fibrosis of the bile ducts, resulting in end‐stage liver disease and reduced …