The Role of Ca2+ Signaling in Aging and Neurodegeneration: Insights from Caenorhabditis elegans Models

J Alvarez, P Alvarez-Illera, P García-Casas, RI Fonteriz… - Cells, 2020 - mdpi.com
Ca2+ is a ubiquitous second messenger that plays an essential role in physiological
processes such as muscle contraction, neuronal secretion, and cell proliferation or …

Caenorhabditis elegans as an emerging model in food and nutrition research: importance of standardizing base diet

Y Wang, K Guo, Q Wang, G Zhong… - Critical Reviews in …, 2024 - Taylor & Francis
As a model organism that has helped revolutionize life sciences, Caenorhabditis elegans
has been increasingly used in nutrition research. Here we explore the tradeoffs between …

Sink or swim: Does a worm paralysis phenotype hold clues to neurodegenerative disease?

P Rodriguez, RD Blakely - Journal of Cellular Physiology, 2024 - Wiley Online Library
Receiving a neurodegenerative disease (NDD) diagnosis, such as Alzheimer's disease,
Parkinson's disease, Huntington's disease, or amyotrophic lateral sclerosis, is devastating …

Targeted Central Nervous System Irradiation of Caenorhabditis elegans Induces a Limited Effect on Motility

M Suzuki, Z Soh, H Yamashita, T Tsuji, T Funayama - Biology, 2020 - mdpi.com
To clarify the tissue responsible for a biological function, that function can be experimentally
perturbed by an external stimulus, such as radiation. Radiation can be precisely and finely …

Functional analysis of epilepsy‐associated GABAA receptor mutations using Caenorhabditis elegans

A Gadhia, E Barker, A Morgan, JW Barclay - Epilepsia Open, 2024 - Wiley Online Library
Objective GABAA receptor subunit mutations pose a significant risk for genetic generalized
epilepsy; however, there are over 150 identified variants, many with unknown or unvalidated …

Immune dysfunction and multiple treatment modalities for the SARS-CoV-2 pandemic: races of uncontrolled running sweat?

A Kothari, V Singh, UK Nath, S Kumar, V Rai… - Biology, 2020 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a global pandemic
threat with more than 11.8 million confirmed cases and more than 0.5 million deaths as of 3 …

[HTML][HTML] Molecular tools for targeted control of nerve cell electrical activity. Part I

DV Kolesov, EL Sokolinskaya, KA Lukyanov… - Acta …, 2021 - ncbi.nlm.nih.gov
In modern life sciences, the issue of a specific, exogenously directed manipulation of a cell's
biochemistry is a highly topical one. In the case of electrically excitable cells, the aim of the …

[HTML][HTML] Молекулярные инструменты направленного контроля электрической активности нервных клеток. Часть II

ДВ Колесов, ЕЛ Соколинская… - Acta Naturae …, 2021 - cyberleninka.ru
Проблема специфического воздействия на биохимические процессы в клетке
актуальна для современной биологической науки. В случае электровозбудимых клеток …

Распознающие cкаффолдовые полипептиды как инструмент для адресной доставки наноструктур in vitro и in vivo

ВО Шипунова, СМ Деев - elibrary.ru
Традиционные средства адресной доставки наноструктур, такие, как антитела,
трансферрин, лектины или аптамеры, зачастую могут вызывать целый спектр …

[PDF][PDF] ASSESSING THE IMPACTS OF AMPHETAMINE EXPOSURE FOLLOWING SELECTIVE ABLATION OF DOPAMINERGIC NEURONS VIA THE FLUORESCENT …

GD Byrd - 2021 - fau.digital.flvc.org
ASSESSING THE IMPACTS OF AMPHETAMINE EXPOSURE FOLLOWING SELECTIVE
ABLATION OF DOPAMINERGIC NEURONS VIA THE FLUORESCENT PROTEIN, Page 1 …