Reactive oxygen species-responsive gel-based microneedle patches for prolonged and intelligent psoriasis management

D Bi, F Qu, W Xiao, J Wu, P Liu, H Du, Y Xie, H Liu… - ACS …, 2023 - ACS Publications
Psoriasis is an inflammatory skin disease. Microneedle (MN) patches can improve psoriasis
treatment outcomes by increasing local drug content in the skin. As psoriasis frequently …

Transdermal hormone delivery: Strategies, application and modality selection

C Xu, Y Wu, L Zhao, W Zhou, Y Li, X Yi, Y Wang… - Journal of Drug Delivery …, 2023 - Elsevier
There is a wide range of hormonal drugs and they are effective in conditions such as
diabetes, atopic dermatitis, psoriasis, and rheumatoid arthritis. The current routes of …

Chitosan-Grafted-Poly(N-vinylcaprolactam)-Decorated Fe3O4@SiO2 Core–Shell Nanoformulation as an Efficient Drug Delivery System for Poorly Soluble Drugs

S Asgari, B Farasati Far, G Charmi… - ACS Applied Bio …, 2023 - ACS Publications
Hydrocortisone, a commonly used anti-inflammatory drug, has limited aqueous solubility
and several side effects. To address this challenge, as a proof-of-concept, this article …

Unveiling hydrogel's prominence: a breakthrough in topical formulations for psoriasis treatment

P Dutt, G Singhvi, Y Tomar, S Sain… - International Journal of …, 2024 - Taylor & Francis
Psoriasis is chronic autoimmune inflammatory skin disorder affecting millions of people
worldwide (2–3% of world population). Treatment of psoriasis ranges from use of topicals to …

Hydrocortisone-Loaded Lipid–Polymer Hybrid Nanoparticles for Controlled Topical Delivery: Formulation Design Optimization and In Vitro and In Vivo Appraisal

OA Alsaidan, M Elmowafy, K Shalaby, SI Alzarea… - ACS …, 2023 - ACS Publications
The barrier functionalities of the skin offer a major but not insuperable hindrance for
fabrication of skin delivery effective systems. This work aimed to develop an optimized lipid …

[HTML][HTML] Biomineralized in situ catalytic nanoreactor integrated microneedle patch for on demand immunomodulator supply to combat psoriasis

X Li, M Chen, X He, J Cong, W Zhao, Y Fu, C Lu… - …, 2024 - pmc.ncbi.nlm.nih.gov
The endogenous immunomodulator adenosine (ADO) was expected to be potentialized as
an efficacious mediator to combat psoriasis. However, its efficacy is severely hindered by its …

Design and Biocompatibility of Biodegradable Poly (octamethylene suberate) Nanoparticles to Treat Skin Diseases

DPC de Barros, LP Fonseca, LG Gonçalves… - Pharmaceutics, 2024 - mdpi.com
Biodegradable aliphatic polyester formulations as carriers for topical drug delivery show the
potential to encapsulate structurally different therapeutic compounds. Poly (octamethylene …

Piperine Extraction and Encapsulation in Polycaprolactone Nanoparticles

JC Coco, LAL Silvério, ÉM Santos, AC Sueiro… - Cosmetics, 2023 - mdpi.com
Black pepper, a commonly utilized culinary condiment, holds significant importance in
Ayurvedic and Chinese medicinal practices due to its various biological benefits, including …

Formulation and Characterization of Non-Toxic, Antimicrobial, and Alcohol-Free Hand Sanitizer Nanoemulgel Based on Lemon Peel Extract

FM Ibrahim, ES Shalaby, MA El-Liethy… - Cosmetics, 2024 - mdpi.com
Recently, hand sanitization has gained attention for preventing disease transmission. Many
on-the-market convenient dermal sanitizers contain alcohol, which can be detrimental to the …

Nanoscale topical pharmacotherapy in management of psoriasis: Contemporary Research and scope

MZ Ahmad, AA Mohammed, MS Algahtani… - Journal of Functional …, 2022 - mdpi.com
Psoriasis is a typical dermal condition that has been anticipated since prehistoric times
when it was mistakenly implicit in being a variant of leprosy. It is an atypical organ-specific …