To cite this article: Detoraki A, Granata F, Staibano S, Rossi FW, Marone G, Genovese A.
Angiogenesis and lymphangiogenesis in bronchial asthma. Allergy 2010; 65: 946–958 …

The clinical and pathologic features of eosinophilic esophagitis (EE) include extensive
tissue remodeling. Increasing evidence supports a key role for the eosinophil in multiple …

BACKGROUND: The airway epithelium can express factors that drive subepithelial airway
remodeling. TGF-β2, vascular epithelial growth factor (VEGF), a disintegrin and …

Rationale: Angiogenesis is a defining pathologic feature of airway remodeling and
contributes to asthma severity. Women experience changes in asthma control over the …

Allergic asthma is a complex chronic inflammatory disease of the airways, driven by Th2
immune responses and characterized by eosinophilic pulmonary inflammation, airway …

Bronchial asthma and chronic obstructive pulmonary disease (COPD) remain a global
health problem with significant morbidity and mortality. The changes in bronchial …

Asthma imposes a heavy morbidity burden during childhood; it affects over 10% of children
in Europe and North America and it is estimated to exceed 400 million people worldwide by …

Human airway smooth muscle cells (HASMC) contribute to asthma pathophysiology through
an increased smooth muscle mass and elevated cytokine/chemokine output. Little is known …

We observed a significant increase in CANO values in healthy children and adolescents age
10 to 19 years compared with published data in healthy subjects aged 20 to 39 years, as …

In response to hypoxia, adaptive hypoxia-inducible factor-1 (HIF-1) signaling events are
activated to increase oxygen transport, anaerobic energy production and protective …