The role of oxidative stress in skeletal muscle myogenesis and muscle disease

D Lian, MM Chen, H Wu, S Deng, X Hu - Antioxidants, 2022 - mdpi.com
The contractile activity, high oxygen consumption and metabolic rate of skeletal muscle
cause it to continuously produce moderate levels of oxidant species, such as reactive …

The role of oxidative stress in skeletal muscle injury and regeneration: focus on antioxidant enzymes

M Kozakowska, K Pietraszek-Gremplewicz… - Journal of muscle …, 2015 - Springer
Reactive oxygen species (ROS) are generated in skeletal muscle both during the rest and
contractile activity. Myogenic cells are equipped with antioxidant enzymes, like superoxide …

Glutathione peroxidase GPX1 and its dichotomous roles in cancer

Y Zhao, H Wang, J Zhou, Q Shao - Cancers, 2022 - mdpi.com
Simple Summary Glutathione peroxidase 1 (GPX1), as one of the most important antioxidant
enzymes, maintains cellular redox balance by regulating reactive oxygen species levels. In …

[HTML][HTML] Reactive oxygen species: impact on skeletal muscle

SK Powers, LL Ji, AN Kavazis… - Comprehensive …, 2011 - ncbi.nlm.nih.gov
It is well established that contracting muscles produce both reactive oxygen and nitrogen
species. Although the sources of oxidant production during exercise continue to be debated …

When is an antioxidant not an antioxidant? A review of novel actions and reactions of vitamin C

TL Duarte, J Lunec - Free Radic Res, 2005 - search.ebscohost.com
Vitamin C (or ascorbic acid) is regarded as the most important water-soluble antioxidant in
human plasma and mammalian cells which have mechanisms to recycle and accumulate it …

Mediators of physical activity protection against ROS-linked skeletal muscle damage

S Di Meo, G Napolitano, P Venditti - International journal of molecular …, 2019 - mdpi.com
Unaccustomed and/or exhaustive exercise generates excessive free radicals and reactive
oxygen and nitrogen species leading to muscle oxidative stress-related damage and …

Modulation of skeletal muscle antioxidant defense by exercise: Role of redox signaling

LL Ji - Free Radical Biology and Medicine, 2008 - Elsevier
Contraction-induced production of reactive oxygen species has been shown to cause
oxidative stress to skeletal muscle. As an adaptive response, muscle antioxidant defense …

ERK1/2 and p38-MAPK signalling pathways, through MSK1, are involved in NF-κB transactivation during oxidative stress in skeletal myoblasts

E Kefaloyianni, C Gaitanaki, I Beis - Cellular signalling, 2006 - Elsevier
Skeletal muscle is highly adapted to respond to oxidative imbalances, since it is
continuously subjected to an increased production of reactive oxygen species (ROS) during …

NF-κB signaling: a tale of two pathways in skeletal myogenesis

N Bakkar, DC Guttridge - Physiological reviews, 2010 - journals.physiology.org
NF-κB is a ubiquitiously expressed transcription factor that plays vital roles in innate
immunity and other processes involving cellular survival, proliferation, and differentiation …

Effects of aerobic exercise training on antioxidant enzyme activities and mRNA levels in soleus muscle from young and aged rats

RH Lambertucci, AC Levada-Pires, LV Rossoni… - Mechanisms of ageing …, 2007 - Elsevier
The aim of this study was to investigate the effect of aerobic exercise training on activities
and mRNA levels of catalase (CAT), glutathione peroxidase (GPX), Cu, Zn-and Mn …