Cancer remains to be one of the leading causes of death in the United States and around
the world. The advent of modern drug-targeted therapies has undeniably improved cancer …

Pyrazolone is a well-known influential synthon for the synthesis of many molecules which
hold remarkable potential in the advancement of functional materials, coordination …

Chronic inflammatory mediators exert pleiotropic effects in the development of cancer. On
the one hand, inflammation favors carcinogenesis, malignant transformation, tumor growth …

Multidrug-resistant infections have placed a financial and health burden on the health-care
system and population. As a result, human health was faced major issues due to multidrug …

COX-2, a key enzyme that catalyzed the rate-limiting steps in the conversion of arachidonic
acid to prostaglandins, played a pivotal role in the inflammatory process. Different from other …

Many marine-derived polysaccharides and their analogues have been reported as showing
anticancer and cancer preventive properties. These compounds demonstrate interesting …

Chronic inflammation has emerged as one of the hallmarks of cancer. Inflammation also
plays a pivotal role in modulating radiation responsiveness of tumors. As discussed in this …

Inadequate vitamin D status has been linked to increased risk of type 2 diabetes and
cardiovascular disease. Inducible cyclooxygenase (COX) isoform COX-2 has been involved …

Abstract Cyclooxygenase 2 (COX-2) and the production of cytokines/chemokines are
important targets for the modulation of the inflammatory response. Although a large variety of …

Cancer is the second leading cause of death worldwide. There is greater need for more
effective and less toxic therapeutic and preventive strategies. Natural products are becoming …