Biomarker-driven molecular imaging probes in radiotherapy
Background: Biomarker-driven molecular imaging has emerged as an integral part of cancer
precision radiotherapy. The use of molecular imaging probes, including nanoprobes, have …
precision radiotherapy. The use of molecular imaging probes, including nanoprobes, have …
Meningioma: International Consortium on Meningiomas consensus review on scientific advances and treatment paradigms for clinicians, researchers, and patients
Meningiomas are the most common primary intracranial tumors in adults and are increasing
in incidence due to the aging population and increased access to neuroimaging. While most …
in incidence due to the aging population and increased access to neuroimaging. While most …
Molecular classification to refine surgical and radiotherapeutic decision-making in meningioma
Abstract Treatment of the tumor and dural margin with surgery and sometimes radiation are
cornerstones of therapy for meningioma. Molecular classifications have provided insights …
cornerstones of therapy for meningioma. Molecular classifications have provided insights …
Perivascular NOTCH3+ Stem Cells Drive Meningioma Tumorigenesis and Resistance to Radiotherapy
Meningiomas are the most common primary intracranial tumors. Treatments for patients with
meningiomas are limited to surgery and radiotherapy, and systemic therapies remain …
meningiomas are limited to surgery and radiotherapy, and systemic therapies remain …
cIMPACT-NOW Update 8: Clarifications on molecular risk parameters and recommendations for WHO grading of meningiomas
Meningiomas are the most frequent primary intracranial tumors. Hence, they constitute a
major share of diagnostic specimens in neuropathology practice. The 2021 WHO …
major share of diagnostic specimens in neuropathology practice. The 2021 WHO …
Spatial genomic, biochemical and cellular mechanisms underlying meningioma heterogeneity and evolution
Intratumor heterogeneity underlies cancer evolution and treatment resistance, but targetable
mechanisms driving intratumor heterogeneity are poorly understood. Meningiomas are the …
mechanisms driving intratumor heterogeneity are poorly understood. Meningiomas are the …
[HTML][HTML] Meningioma transcriptomic landscape demonstrates novel subtypes with regional associated biology and patient outcome
HN Thirimanne, D Almiron-Bonnin, N Nuechterlein… - Cell genomics, 2024 - cell.com
Meningiomas, although mostly benign, can be recurrent and fatal. World Health
Organization (WHO) grading of the tumor does not always identify high-risk meningioma …
Organization (WHO) grading of the tumor does not always identify high-risk meningioma …
RNA splicing as a biomarker and phenotypic driver of meningioma DNA-methylation groups
Background Advances in our understanding of the molecular biology of meningiomas have
led to significant gains in the ability to predict patient prognosis and tumor recurrence and to …
led to significant gains in the ability to predict patient prognosis and tumor recurrence and to …
Grade-stratified meningioma risk among individuals who are non-Hispanic Black and interactions with male sex
KM Walsh, M Price, DR Raleigh… - JNCI: Journal of the …, 2024 - academic.oup.com
Background Meningioma risk factors include older age, female sex, and being Black/African
American. Limited data explore how meningioma risk in individuals who are Black varies …
American. Limited data explore how meningioma risk in individuals who are Black varies …
Efficacy and toxicity of bimodal radiotherapy in WHO grade 2 meningiomas following subtotal resection with carbon ion boost: prospective phase 2 MARCIE trial
Background Novel radiotherapeutic modalities using carbon ions provide an increased
relative biological effectiveness (RBE) compared to photons, delivering a higher biological …
relative biological effectiveness (RBE) compared to photons, delivering a higher biological …