DNA, mRNA and microRNA are released and circulate in the blood of cancer patients.
Changes in the levels of circulating nucleic acids have been associated with tumour burden …

Synthetic biology is a research field that combines the investigative nature of biology with
the constructive nature of engineering. Efforts in synthetic biology have largely focused on …

Quinoline (1-azanaphthalene) is a heterocyclic aromatic nitrogen compound characterized
by a double-ring structure that contains a benzene ring fused to pyridine at two adjacent …

Every year more than 13 million deaths worldwide are due to environmental pollutants, and
approximately 24% of diseases are caused by environmental exposures that might be …

S-Adenosyl-L-methionine (SAM) is a sulfonium molecule with a structural hybrid of
methionine and adenosine. As the second largest cofactor in the human body, its major …

Romidepsin (Istodax), a selective inhibitor of histone deacetylases (HDACs), was approved
for the treatment of cutaneous T-cell lymphoma in November 2009 by the US Food and Drug …

Histone deacetylases (HDACs) can regulate expression of tumor suppressor genes and
activities of transcriptional factors involved in both cancer initiation and progression through …

Heavy metals that are harmful to humans include arsenic, cadmium, chromium, lead,
mercury, and nickel. Some metals or their related compounds may even cause cancer …

Cancer, as one of the non-communicable diseases, remains one of the leading causes of
death around the world. Recently, epigenetic changes in DNA methylation patterns at CpG …

Simple, rapid, and sensitive technologies to detect nucleic acid modifications have important
applications in genetic analysis, clinical diagnosis, and molecular biology. Because genetic …