Post-translational modifications (PTM) involve enzyme-mediated covalent addition of
functional groups to proteins during or after synthesis. These modifications greatly increase …

Physical, chemical and biological stress factors, such as microbial infection, upregulate the
transcription levels of a number of plant genes, coding for the so‐called pathogenesis …

A new strategy for predicting the topology of bacterial inner membrane proteins is proposed
on the basis of hydrophobicity analysis, automatic generation of a set of possible topologies …

A new method for identifying secretory signal sequences and for predicting the site of
cleavage between a signal sequence and the mature exported protein is described. The …

POSITIVELY charged amino acids have been shown to be important elements in targeting-
peptides that direct proteins into mitochon-dria, nuclei, and the secretory pathways of both …

Twenty three mitochondrial targeting sequences have been analysed with regard to their
potential for forming amphiphilic helices. It is shown that most if not all of these sequences …

Representative samples of mitochondrial and chloroplast targetting peptides have been
analyzed in terms of amino acid composition, positional amino acid preferences and …

Nα-terminal acetylation occurs in the yeast Saccharomyces cerevisiae by any of three N-
terminal acetyltransferases (NAT), NatA, NatB, and NatC, which contain Ard1p, Nat3p and …

Our previous work has shown that, in the yeast Saccharomyces cerevisiae, any of the eight
stabilizing amino-terminal residues confers a long (> 20 h) half-life on a test protein β …

Methionine aminopeptidase (MAP) is a ubiquitous, essential enzyme involved in protein N-
terminal methionine excision. According to the generally accepted cleavage rules for MAP …