[HTML][HTML] Drug discovery and development targeting the life cycle of SARS-CoV-2
H Su, Y Xu, H Jiang - Fundamental Research, 2021 - Elsevier
A newly emerged coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2), belongs to the β-coronavirus family and shows high similarities with SARS-CoV. On …
CoV-2), belongs to the β-coronavirus family and shows high similarities with SARS-CoV. On …
The effect of various compounds on the COVID mechanisms, from chemical to molecular aspects
S Mahmoudi, MM Dehkordi, MH Asgarshamsi - Biophysical Chemistry, 2022 - Elsevier
The novel coronavirus that caused COVID-19 pandemic is SARS-CoV-2. Although various
vaccines are currently being used to prevent the disease's severe consequences, there is …
vaccines are currently being used to prevent the disease's severe consequences, there is …
3-Alkenyl-2-oxindoles: Synthesis, antiproliferative and antiviral properties against SARS-CoV-2
Abstract Sets of 3-alkenyl-2-oxindoles (6, 10, 13) were synthesized in a facile synthetic
pathway through acid dehydration (EtOH/HCl) of the corresponding 3-hydroxy-2 …
pathway through acid dehydration (EtOH/HCl) of the corresponding 3-hydroxy-2 …
Antiviral activities of natural compounds and ionic liquids to inhibit the Mpro of SARS-CoV-2: a computational approach
The recalcitrant spread of the COVID-19 pandemic produced by the novel coronavirus
SARS-CoV-2 is one of the most destructive occurrences in history. Despite the availability of …
SARS-CoV-2 is one of the most destructive occurrences in history. Despite the availability of …
[PDF][PDF] Losartan inhibits SARS-CoV-2 replication in vitro
R Nejat, AS Sadr, BT Freitas… - … of Pharmacy and …, 2021 - frontierspartnerships.org
Purpose: SARS-CoV-2 infection is associated with substantial mortality and high morbidity.
This study tested the effect of angiotensin II type I receptor blocker, losartan, on SARS-CoV-2 …
This study tested the effect of angiotensin II type I receptor blocker, losartan, on SARS-CoV-2 …
Solar energy assisted thermal treatment model to decontaminate airborne viruses in hospital
The evolution of airborne viruses across the globe has caused many deaths in recent
decades. Currently, the world is witnessing the terrible behavior of SARS-CoV-2. The …
decades. Currently, the world is witnessing the terrible behavior of SARS-CoV-2. The …
[PDF][PDF] Traditional Chinese medicine: an important broad-spectrum anti-coronavirus treatment strategy on COVID-19 background?
Coronaviruses exist widely in nature, can cause cross-species transmission, and pose
serious threats to human and animal health. Over the past 20 years, coronaviruses have led …
serious threats to human and animal health. Over the past 20 years, coronaviruses have led …
Enhanced compound-protein binding affinity prediction by representing protein multimodal information via a coevolutionary strategy
Due to the lack of a method to efficiently represent the multimodal information of a protein,
including its structure and sequence information, predicting compound-protein binding …
including its structure and sequence information, predicting compound-protein binding …
Inhibition of SARS-CoV-2 main protease: a repurposing study that targets the dimer interface of the protein
Abstract Coronavirus disease-2019 (COVID-19) was firstly reported in Wuhan, China,
towards the end of 2019, and emerged as a pandemic. The spread and lethality rates of the …
towards the end of 2019, and emerged as a pandemic. The spread and lethality rates of the …
The serendipitous integration of small boron-embedded molecules into medicinal chemistry
F Abi-Ghaida - Fundamentals and applications of boron chemistry, 2022 - Elsevier
Despite the forte of organic medicinal chemistry, impediments as the dreaded drug-
resistance phenomenon necessitate forging alternative drugs equipped with unorthodox …
resistance phenomenon necessitate forging alternative drugs equipped with unorthodox …