As an essential vitamin, the role of riboflavin in human diet and health is increasingly being
highlighted. Insufficient dietary intake of riboflavin is often reported in nutritional surveys and …

Riboflavin is classified as one of the water-soluble B vitamins. It is part of the functional
group of flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) cofactors and …

To attain functionality, proteins must fold into their three-dimensional native state. The
intracellular balance between protein synthesis, folding, and degradation is constantly …

Abstract Background Mitochondrial acyl-CoA dehydrogenase family member 9 (ACAD9) is
essential for the assembly of mitochondrial respiratory chain complex I. Disease causing …

Protein misfolding has been linked to numerous inherited diseases. Loss‐and gain‐of‐
function mutations (common features of genetic diseases) may cause the destabilization of …

Heart failure (HF) is a plague of the aging population in industrialized countries that
continues to cause many deaths despite intensive research into more effective treatments …

The primary role of the water-soluble vitamin B2, ie riboflavin, in cell biology is connected
with its conversion into FMN and FAD, the cofactors of a large number of dehydrogenases …

Abstract NAD (P) H quinone oxidoreductase 1 is involved in antioxidant defence and
protection from cancer, stabilizing the apoptosis regulator p53 towards degradation. Here …

Fatty acids are a major fuel for the body and fatty acid oxidation is particularly important
during fasting, sustained aerobic exercise and stress. The myocardium and resting skeletal …

Oxidative phosphorylation and fatty acid oxidation are two major metabolic pathways in
mitochondria. Acyl-CoA dehydrogenase 9 (ACAD9), an enzyme assumed to play a role in …