Phylogenetic and phylodynamic approaches to understanding and combating the early SARS-CoV-2 pandemic

SW Attwood, SC Hill, DM Aanensen… - Nature Reviews …, 2022 - nature.com
Determining the transmissibility, prevalence and patterns of movement of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infections is central to our understanding …

Therapeutic targets and interventional strategies in COVID-19: mechanisms and clinical studies

YW Zhou, Y Xie, LS Tang, D Pu, YJ Zhu… - Signal transduction and …, 2021 - nature.com
Owing to the limitations of the present efforts on drug discovery against severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) and the lack of the understanding of the …

[HTML][HTML] SARS-CoV-2 variants B. 1.351 and P. 1 escape from neutralizing antibodies

M Hoffmann, P Arora, R Groß, A Seidel, BF Hörnich… - Cell, 2021 - cell.com
The global spread of SARS-CoV-2/COVID-19 is devastating health systems and economies
worldwide. Recombinant or vaccine-induced neutralizing antibodies are used to combat the …

Genomics and epidemiology of the P. 1 SARS-CoV-2 lineage in Manaus, Brazil

NR Faria, TA Mellan, C Whittaker, IM Claro… - Science, 2021 - science.org
Cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in
Manaus, Brazil, resurged in late 2020 despite previously high levels of infection. Genome …

The N501Y spike substitution enhances SARS-CoV-2 infection and transmission

Y Liu, J Liu, KS Plante, JA Plante, X Xie, X Zhang, Z Ku… - Nature, 2022 - nature.com
Abstract The B. 1.1. 7 variant (also known as Alpha) of SARS-CoV-2, the cause of the COVID-
19 pandemic, emerged in the UK in the summer of 2020. The prevalence of this variant …

[HTML][HTML] T-cell and antibody responses to first BNT162b2 vaccine dose in previously infected and SARS-CoV-2-naive UK health-care workers: a multicentre …

A Angyal, S Longet, SC Moore, RP Payne… - The Lancet …, 2022 - thelancet.com
Background Previous infection with SARS-CoV-2 affects the immune response to the first
dose of the SARS-CoV-2 vaccine. We aimed to compare SARS-CoV-2-specific T-cell and …

[HTML][HTML] An overview of current COVID-19 vaccine platforms

A Nagy, B Alhatlani - Computational and structural biotechnology journal, 2021 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the
coronavirus disease 2019 (COVID-19) pandemic that emerged in December 2019 in Wuhan …

[HTML][HTML] The N501Y spike substitution enhances SARS-CoV-2 transmission

Y Liu, J Liu, KS Plante, JA Plante, X Xie, X Zhang, Z Ku… - BioRxiv, 2021 - ncbi.nlm.nih.gov
Beginning in the summer of 2020, a variant of SARS-CoV-2, the cause of the COVID-19
pandemic, emerged in the United Kingdom (UK). This B. 1.1. 7 variant increased rapidly in …

[HTML][HTML] SARS-CoV-2 Delta (B. 1.617. 2) variant: a unique T478K mutation in receptor binding motif (RBM) of spike gene

H Jhun, HY Park, Y Hisham, CS Song, S Kim - Immune network, 2021 - ncbi.nlm.nih.gov
Over two hundred twenty-eight million cases of coronavirus disease 2019 (COVID-19) in the
world have been reported until the 21 st of September 2021 after the first rise in December …

SARS-CoV-2 variants B. 1.351 and B. 1.1. 248: Escape from therapeutic antibodies and antibodies induced by infection and vaccination

M Hoffmann, P Arora, R Groß, A Seidel, B Hörnich… - BioRxiv, 2021 - biorxiv.org
The global spread of SARS-CoV-2/COVID-19 is devastating health systems and economies
worldwide. Recombinant or vaccine-induced neutralizing antibodies are used to combat the …